PubMed Health⌕ Search

Biomedical subjects

I D Kirpatovskiĭ

Publications and source records attributed to I D Kirpatovskiĭ.

At least 19 recordsLinked to original sources
PubMed1999

[Ultrastructural changes of veins in several variants of cryopreservation].

The findings of ultrastructural analysis demonstrated essential changes in connective tissue cells and noncellular elements of veins after their cryopreservation at -50 degrees C and -196 degrees C. Contraction and round-up of endotheliocytes, disruption of their connections with basement membrane leading to subendothelial space widening, cytoplasm vacuolization and focal destruction of luminal plasmalemma are typical and general changes caused by cryopreservation. Dystrophy of different grades developed in connective tissues of media and adventitia. Deeper freezing negatively affects structural integrity of venous tissues. After the use of conserving solutions (Eurocollins and Scientific Research Institute of Traumatology and Orthopaedics) necrotized endotheliocytes were absent and endothelial lining was preserved in major part of the vein surface studied even following its deep freezing which supports the conclusion on the cryoprotective effect of the solutions.

Animals↗
PubMed1994

[Allotransplantation of cultured neonatal androgen-producing Leydig cells].

The paper describes the procedure for grafting the cultural neonatal androgen-producing Leydig's cells to the rat gonad, the status of the gonad and the graft in different periods following transplantation. The transplanted Leydig's cells preserve their structure within 6 months after allotransplantation. There is a normal spermatogenesis in the seminal canals. No phenomena of lymphoid infiltration, thrombosis of small vessels and other manifestations of histocompatibility were noted.

Androgens↗
PubMed1991

[A method of obtaining radial skin flap on a vascular-neural pedicle from the forearm].

The authors examined 65 adult cadavers in which they studied vascularization of a radial skin flap of the forearm and conducted an anatomical experiment of its preparation. The vascularization boundaries were studied as well as the peculiarities of preparation of a radial skin flap of the forearm with a precise approach to a vascular-neural pedicle and maximal preservation of cutaneous branches arising from the radial artery.

Adult↗
PubMed1991

[Secretory activity of endocrine glands in gastroduodenal ulcer during late postoperative period].

The hormonal status of the endocrine glands (the hypophysis, thyroid, adrenals, pancreas, gastrin-producing cells of the stomach, gonads), was evaluated in patients with gastroduodenal ulcer operated (gastric resection, vagotomy) 6, 12 or 36 months before. Hormonal balance was found affected, the gonads underwent gross changes responsible for gonadal depletion in the long-term postoperative period. Recommendations for relevant correction are provided.

Adolescent↗
PubMed1991

[Analysis of morphologic classifications of testicular lesions in male sterility].

An analysis of the authors' own data based on the examination of 697 testis biopsies is given. The material is subdivided into two groups depending on the presence or absence of germ cells: 1) hypospermatogenesis and 2) aspermatogenesis. Hypospermatogenesis is related to any tubule changes resulting in the under-production of spermatozoa. Criteria of tubule changes and a method for determination of the hypospermatogenesis degree are given. Insolvency of some existing histologic classifications is shown.

Humans↗
PubMed1990

[Transplantation of immature allogeneic testis].

Experimental and clinical studies (109 rat and 17 dog experiments and four clinical transplantations of a neonatal testis to children with the postcastration syndrome and postnatal hypoplasia of their own testes) showed that transplantation of an immature testis makes it possible to reduce to maximum its damage on exposure to the effect of unspecific and specific factors of transplantation. The transplantation ensures prolonged viability and function of the allogeneic male sexual gland, which is confirmed by the maintenance of its specific structures (the ultrastructural level among others) in the late-term postoperative period, the ability of immature allogeneic transplants to restore the sexual behaviour of castrated animal recipients, and by the positive results of clinical test of the method.

Animals↗
PubMed1989

[Selective action of chorionic gonadotropin on lymphocyte subpopulations].

Influence of chorionic gonadotropin on induction and formation of specific T-suppressors, TDTH-effectors and spontaneous killer cells, depending on its doses and schema of injections was studied. It is shown that chorionic gonadotropin has a stimulating effect on precursors of T-suppressors, not affecting the mature specific T-suppressors, causes damage to the TDTH-effectors and spontaneous killer cells, that permits chorionic gonadotropin to be recognized as an immunomodulating agent.

Animals↗
PubMed1989

[Intraorganic blood vessels of the intestinal graft after its ortho- and heterotopic transplantation].

In experiments, performed on 85 dogs of both sex ortho- and heterotopic total autotransplantation of the small intestine and extracorporal connection of the allogenic segments of the small intestine have been carried out. Certain dependency of morphological changes of the intraorganic blood bed on the operation model has been stated. Essential changes in the blood bed at the heterotopic autotransplantation depend on inadequate regional hemodynamics in the graft. Therefore, the heterotopic model should be considered less preferable than the orthotopic one. One of the peculiarities in reconstruction of the intraorganic vascular bed after ortho- and heterotropic transplantation of the small intestine is, evidently, opening of lympho-venular anastomoses.

Animals↗
PubMed1987

[Anatomical basis for vascular-pedicle transplantation of the hypothalamo-hypophyseal complex].

In 240 corpses of mature persons by means of complex morphological methods extraorganic arteries of the hypophysis, anterior hypothalamus have been investigated, as well as topography of the arterial peduncle of the hypothalamo-hypophyseal complex. Blood supply of the hypophysis and of the anterior hypothalamic part is performed from one common vascular pool--the arterial ring of the brain via multiple arterial branches, their amount and diameter varying considerably. Taking into account an important role of anastomotic vessels and numerous arterial plexuses, when the hypothalamo-hypophyseal complex is extirpated for investigation, it is necessary to include into its composition, besides the major arterial peduncle, the optic chiasm, the grey tuber and the system of cavernous sinuses. Owing to this, there is no need to separate the arterial peduncle of the transplant at the moment of obtaining the hypothalamo-hypophyseal complex. The topographic anatomical investigations performed make prerequisites for transplantation of the hypothalamo-hypophyseal complex on the vascular peduncle in clinic.

Adult↗
PubMed1986

[Transport function of lymphovenous anastomosis].

The work is devoted to functional methods of examination of the lymphatic system in operations for the formation of lymphovenous anastomoses. The method of "moving bubble" was used for the investigation of the transport function of 50 lymphovenous anastomoses. This method was found to allow determination of the transport function of different variants of lympho-venous and lymphonodular-venous anastomoses, their patency and hermetic capacity and detection of the functionally more advantageous variant of the operation for the introduction into practice.

Animals↗