Biomedical subjects
Publications and source records attributed to I D Loranskaia.
The diagnostic capacities of the breath hydrogen test in gastroenterology are discussed in the article. The authors describe the results of their own research--determination of the intestinal bacterial contamination in patients with chronic biliary pancreatitis with the help of the Micro H2 breath hydrogen analyzer.
For the last few years the disorders of the motor function of the gastrointestinal tract are subjects of interest for investigators and physicians. The article presents an analysis of different abnormalities of the motor function of the stomach and duodenum made by gastroduodenoscintigraphy in patients with the biliary tract disorders. The most frequent types of motor gastric and duodenal dysfunctions are discussed in patients with gall bladder dysfunction, chronic cholescystitis, and patients after cholecystectomy.
Ovalbumin loading enzyme immunoassay was made in 44 patients with ulcerative colitis (UC) and 8 patients with Crohn's disease (CD). Enhanced intestinal permeability for macromolecules was found in 87.5 and 65.9% of patients with CD and UC, respectively. Blood serum of UC patients suffering from combination of food intolerance with dysbacteriosis contained ovalbumin in amounts exceeding those in patients without the above disorders 3.4 times (p < 0.05). No significant relationship existed between UC patients' high intestinal permeability and such indices as age, duration of the disease, intestinal lesion extension, administration of corticosteroids. It was found desirable to include ovalbumin intestinal permeability test in examination of UC and CD patients to differentiate treatment policy.
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Study of the morphometrical signs of nonspecific ulcerative colitis and immunocompetent cells of the colonic mucosa and blood facilitates the diagnosis and prognosis of the disease.
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