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Biomedical subjects

I D Muratov

Publications and source records attributed to I D Muratov.

At least 19 recordsLinked to original sources
PubMed1994

[Use of open method of treatment in diffuse purulent peritonitis in children].

Open method of treatment--laparotomy--was used in 22 children with diffuse purulent peritonitis, aged from 1 to 14 years. This permitted to drain adequately the abdominal cavity after the operation, to abolish the intoxication during 2-3 days in the most observations, to eliminate the enteroparesis. The single repeated abdominal cavity sanation was sufficient in 19 (90.5%) children, in 2 she was applied twice. Laparostoma was closed in 17 (80.9%) patients on the 2-3 th day, in 4--on the 4-7 th day after the operation. One child (4.5%) died.

Adolescent↗
PubMed1994

[Hirschsprung's disease in newborns].

The authors examined and treated 52 newborn babies and infants with Hirschsprung's disease. The total form was encountered in 25%, the subtotal in 23.1%, the rectosigmoid in 36.5%, the rectal in 9.6%, and the supraanal in 5.8% of cases. The clinical picture was characterized by retention of meconium (94.2%), regurgitation or vomiting (75%), abdominal distention (100%). Irrigography with calculation of the rectosigmoid ratio was conducted in 35 children, histochemical examination in 46, and histological examination in 38 children. Twenty-four (68.5%) children had the third phase of disturbed proportion of the intestinal bacteria with clinical manifestations of enterocolitis. Emergency decompression of the intestine for low acute intestinal obstruction was carried out in 27 newborn babies. Twenty children were subjected to radical surgery in the first 2-4 months of life. The choice of the operative method was guided by the form of the disease and the length of the aganglionic zone.

Biopsy↗
PubMed1992

[Study of large intestinal microflora in newborns with Hirschsprung disease].

In 35 newborns and children at the age under 4 mos with Hirschsprung's disease, colonic microflora was studied. Disbacteriosis at phase 1 was revealed in 1 (2.9%) child, at phase 2--in 7 (20%), at phase 3--in 27 (77.1%). In acute form of Hirschsprung's disease, in 68.5% of cases, disbacteriosis at phase 3 with the signs of enterocolitis causing acute ileus was revealed. Intestinal perforation against background of enterocolitis developed in 8 cases.

Acute Disease↗
PubMed1991

[Characteristics of histochemical diagnosis of Hirschsprung disease in newborn infants].

The authors had 52 newborns and infants with Hirschsprung's disease under observation. The activity of tissue acetylcholinesterase (ASE) was tested by the Karnovsky-Ruts method in 35 cases. ACE activity was evaluated according to 5 types and a specific "newborn" type was set apart. A positive (42.9%) and weakly positive (28.6%) types of ACE activity prevailed in the neonatal period. Test for ACE activity performed in dynamics in 15 newborns showed gradual accumulation of ACE in the mucosa of the large intestine. In 6 (17.1%) babies a false-negative ACE activity was found, which was encountered in hypogangliosis and long-segmental forms. False-positive reactions were not encountered. Histochemical diagnosis made it possible to recognise Hirschprung's disease of the newborn in 82.9% of cases.

Acetylcholinesterase↗