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PubMed1990

[Hematologic changes in sarcoidosis].

On the basis of the literature authors analyse the importance of the involvement of spleen in sarcoidosis and the haematological changes that follow from this. In a group of patients with sarcoidosis of their own department (more than 1200 patients) they observed 2 women with thrombocytopenic purpura, one woman with thrombo- and leukocytopenia, and one woman with agranulocytosis. They shortly reviewed the previous history of their patients, the disease process, and the results of the treatment. All the four of their patients were given corticosteroid treatment and with this the thrombocytopenia was cured. No relapse was observed. One of the patients they have followed for 25 years, and an other one for 20 years. The patient with agranulocytosis was given corticosteroid, granulocyte concentrate, gammaglobulin, and antibiotics, too. Her status also became settled, and during the 10 years after her first observation we did not notice any relapse. The fourth patient is still being treated.

Adrenal Cortex Hormones↗

PubMed1990

[Non-malignant lymphoid changes in the lung].

The authors diagnosed 5 cases of lymphoid interstitial lymphomas (LIP) and 2 pseudolymphomas among their patient material. 2 of the 5 LIP patients were men, whereas 3 were women. One of the patients was a 9-year old girl at the time of diagnosis. In all the 5 cases the disease was verified by means of the histological findings on biopsy of the lung. The patients were treated with corticosteroid, in one case with corticosteroid + cytostatic. The condition of 4 patients improved significantly; they were finally free from complaints. A definite regression was seen on x-ray film. The 5th patient (a woman) is still undergoing treatment at the time of writing. Of the 2 patients with pseudolymphoma, one was male and the other one female. The woman patient is still alive 14 years after the disease had been diagnosed. She received steroid and cytostatic treatment, and she is in a good condition. The male patient died 13 years after the disease had been confirmed, but his death was caused by another disease. He had been given telecobalt therapy. The authors discuss on the basis of two disease patterns the non-malignant lung changes and their differential diagnosis.

Adult↗