Amniotic-fluid alpha-fetoprotein in the antenatal diagnosis of spina bifida.
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Biomedical subjects
Publications and source records attributed to I Donald.
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A technique has been developed for the ultrasonic investigation of renal disease in infants using a specially designed water-bath with a conventional ultrasonic scanner. This permits ultrasonic studies of the renal tract from the neonatal period onwards; the procedure does not distress the child and the water acts as an excellent coupling medium.
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Human lymphocyte cultures were examined for chromosome damage after exposure to ultrasound. Control and treated slides were scored "blind" and showed no evidence of damage due to ultrasound. Neither was there evidence of chromosome damage in blood cultures from six infants whose mothers had ultrasound during pregnancy when compared with that from six infants whose mothers had not. Our results suggest that if diagnostic ultrasound causes chromosome damage it does so with less frequency than acceptable levels of diagnostic x-irradiation.
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