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I Dvoretzky

Publications and source records attributed to I Dvoretzky.

11 recordsLinked to original sources

Primary cutaneous B-cell lymphoma. Diagnosis, treatment, and prognosis.

BACKGROUND: An elderly woman with B-cell lymphoma confined to the skin of the lower extremity was treated with combination chemotherapy and radiation therapy. She relapsed with new skin lesions outside the original radiation port that responded to additional radiation therapy and remains in remission 12 months after her last treatment. OBJECTIVE: This article investigates the diagnosis, treatment, and prognosis of primary cutaneous B-cell lymphoma. METHODS: The relevant literature was researched through computer data bases and bibliographies. RESULTS: Patients who present with localized lesions of primary cutaneous B-cell lymphoma have a favorable prognosis regardless of the type of therapy, although relapses may occur in the absence of systemic disease. CONCLUSION: We advocate the use of local therapies as initial treatment in patients with localized primary cutaneous B-cell lymphoma.

Aged

Human serum and epithelial spread in tissue culture.

The dependence of epithelial spread on human serum in culture has been studied. Using measured pieces of mouse ear skin epithelial outgrowth about floating explants (epiboly) and from adherent explants was studied. Where compared directly the two systems show similar results. Because of its ease of quantitation, the adherent explant culture was studied in greater detail. In this system in the presence of serum appreciable spread was found only after 48 h but spread continued for at least the next 4 days. In the absence of serum only minimal epithelial spread occurred. Adding serum to deficient media enhanced spreading and removing serum from media depressed spreading. The extent of spread appeared independent of mouse age for the first 4-10 weeks though 2-week-old mouse skin showed quantitatively greater spreading. The activity in human serum responsible for epithelial spread acts under conditions of minimal DNA synthesis and is not reproduced by bovine serum albumin, fetuin, or serum that had been exposed to 100 degrees C for 5 min. The activity is not dialyzable and it is resistant to the protease inhibitors DFP and PMSF. These studies suggest that a specific serum component(s) serves to support epithelial spread in vitro.

Age Factors

Fucosidosis.

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Angiokeratoma

Mutilating basal cell epithelioma.

A 49-year-old man was found to have a rare, mutilating basal cell epithelioma of the face. Conventional early therapy with surgery and radiotherapy did not halt the progress of the disease in a hospital environment. The patient died 12 years later.

Basal Cell Carcinoma

Microsporum canis infection: first epidemic in Israel.

We report here on the first epidemic of Microsporum canis infection in Israel. All 78 cases were diagnosed in the port city of Eilat between August, 1975 and May 1976. The epidemic has apparently been controlled with Griseofulvin therapy and public health measures.

Adolescent

Bracelet burn-an unusual electric burn.

A car mechanic sustained a deep partial thickness burn of the wrist when his metal watch strap short circuited the battery of a car upon which he was working.

Adult

Sweating in the 'anhidrotic type' of congenital ectodermal dysplasia.

Whole body sweat rate in two brothers suffering from congenital ectodermal dysplasia (CED) was measured. At a moderate heat load (DBT 30 degrees C and 50% relative humidity) we found no apparent weight loss due to sweating. At a higher heat load (DBT 36 degrees C, 50% relative humidity) sweating was observed, but only at levels approximately two thirds of those observed in normal controls. In the light of these experimental results, we support the suggestion that the nomenclature for CED patients should be changed. Instead of the present classification of anhidrotic CED and hidrotic CED, it is suggested that the terms hypohidrotic and hidrotic be substituted.

Adolescent