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Biomedical subjects

I Egerer

Publications and source records attributed to I Egerer.

At least 19 recordsLinked to original sources
PubMed1986

[Correlation between bleb-like, fingerprint and map-like dystrophy of the cornea].

In epithelial basal membrane dystrophy of the cornea Bron's dystrophy plays a prominent role (frequently combined with fingerprint dystrophy). It can be visualized only in retroillumination, and is without doubt the most common corneal dystrophy. It should be distinguished from Cogan's microcysts, which were seen in only 11% of the authors patients. The incidence of map dystrophy is about the same, while subepithelial plaques are least frequently observed.

Cornea↗
PubMed1986

[Fundus changes in hyperlipidemia].

Of a total of 26 patients with hyperlipidemia, 4 developed flat yellow patches of varying size and shape in the macular area. In a different study a total of 9 subjects with similar flat yellow patches were examined; 6 had increased levels of serum cholesterol and triglycerides. The likelihood that such patients have hyperlipidemia is well over 50%.

Aged↗
PubMed1981

[Serum immunofluorescence examination in loa ophthalmia (author's transl)].

Loaiasis is a chronic parasitic disease caused by the filaria Loa loa.As soon as the worm reaches the subconjunctival space local irration ensues. This so-called Loa ophthalmia necessitates immediate surgical intervention which can be performed under topical anesthesia, using the slit lamp. The indirect immunofluorescence technique represents a valuable diagnostic test,since it is usually difficult to demonstrate the microfilaria in the peripheral blood.

Adult↗
PubMed1981

[Electron-microscopic and biochemical characteristics of pterygia (author's transl)].

Histologically, pterygium is characterized, apart from the presence of typical collagen fibers, by the appearance of fibres which take up elastic stain but differ from normal elastic tissue, as was confirmed by electron-microscopic investigations. Thus, "elastoid degeneration" of collagen is characterized by the loss of the characteristic periodic fibril structure and by the appearance of coiled and knotty fibres. Collagen types in pterygium were identified biochemically for the first time. The main bulk of collagenous tissue consists of 80-90% Type I collagen, while only 10-20% Type III collagen was detected. Type IV collagen (basal membrane collagen) was present in low amounts. Digestion with elastase resulted in 20% solubilization of pterygium, while bacterial collagenase digested up to 40% of the tissue dry weight.

Chemical Phenomena↗
PubMed1980

Erosive-ulcerative herpes simplex blepharitis.

In 28 subjects the diagnosis of an erosive-ulcerative herpes simplex blepharitis was confirmed by laboratory tests. The clinical manifestations were characterized by the presence of erosions of the intermarginal portion of the lid or the presence of skin ulcers located at the lid margin or the combination of both features, and usually by an absence of vesicular eruptions. Erosions of the intermarginal portion of the lid can readily be made visible by staining with fluorescein. The involved lid portion usually exhibits mild swelling and tenderness on palpation. Conjunctival injection usually is not pronounced adjacent to the lid lesion, the regional lymph nodes being swollen. Laboratory confirmation can be achieved readily by the indirect immunofluorescence technique. The treatment modality consists of the combination of antibiotic and virustatic ointments.

Adolescent↗
PubMed1980

[Bleb-like and fingerprint dystrophies of the cornea].

Within the past two years we have seen the "bleb-like dystrophy" of Bron and Brown in 30 patients. It is characterized by groups of subepithelial excrescences measuring 15-100 microms. These pathologic changes can only be discerned biomicroscopically by retro-illumination; they do not result in any opacification of the corneal epithelium or stroma. In 21 cases a concomitant Fingerprint dystrophy of the cornea (Guerry) was observed. Both types of dystrophy were prevalent in female patients and in most cases occurred bilaterally. The relatively high incidence of recurrent erosions as well as the pathologic structure of the subepithelial membrane documented in the Fingerprint dystrophy points to a potential weakness of the corneal epithelium in these cases. This fact should be borne in mind especially when fiting contact lenses.

Adult↗
PubMed1980

[Risks associated with photocoagulation in proliferative diabetic retinopathy (author's transl)].

In 185 diabetics with proliferative diabetic retinopathy (d.r.) involving both eyes symmetrically we analyzed the indication for photocoagulation in borderline cases in which, despite complications (such as inducement of vitreoretinal retraction), the beneficial effect of photocoagulation outweighs the likelihoood of a spontaneous deleterious course. In stage 2 of proliferative d.r. the risks associated with photocoagulation (i.e., factors likely to cause traction phenomena) were found to be extensive coagulation of intraretinal and preretinal hemorrhages, and coagulation of feeder vessels as well as of fundus areas located behind vitreal hemorrhages. In stage 3, procoagulative risk factors in the morphological picture comprised the existence of several vitreoretinal insertions with tent-shaped traction folds and extensive preretinal and subvitreal hemorrhages.

Diabetic Retinopathy↗
PubMed1980

[Branch occlusion of the central retinal artery during coronary angiography (author's transl)].

A 49-year-old man went blind in his left eye during coronary angiography. The following day an occlusion of the inferior temporal and inferior nasal branch of the central retinal artery was detected, associated with a moderate papilledema of the inferior part of the optic disk as well as retinal edema of the inferior fundus. Fluorescein angiography confirmed the clinical diagnosis, perimetry revealed loss of visual field in the superior half. Seven months after the initial examination the patient displayed a partial optic atrophy of the inferior portion of the disk associated with a moderate neovascularization in that area. The visual field loss remained unchanged.

Blindness↗
PubMed1980

[Maplike dystrophy of the cornea (author's transl)].

A report on 11 cases of maplike dystrophy of the cornea; it is characterized by the presence of fine whitish intraepithelial lines, which may easily be overlooked during biomicroscopic examination: they are most easily descernable in bright oblique illumination. Similarities with Cogan's, fingerprint, and bleblike dystrophy (Bron) are discussed, and the potential weakness of the corneal epithelium found in these patients is pointed out.

Aged↗
PubMed1979

[Treatment of herpes simplex of the lid margin with vidarabin ointment (author's transl)].

Twenty cases of herpes simplex of the lid margin were treated with vidarabin ointment applied topically 4 to 5 times daily together with an antibiotic ointment 2 to 4 times per day. Healing of the skin eruptions was observed within 3 to 12 days (average 6 days). Vidarabin eye ointment was well tolerated in all cases. A comparison with other locally-applied virustatic preparations is drawn.

Administration, Topical↗
PubMed1979

[Experimental and clinical experiences with silicone catheters in fistulizing glaucoma surgery].

1. A historical revue of seton operations is presented, which were actually explored for the first time by Rollet in 1907. 2. The paramount importance of the selection of the appropriate material for the setons is stressed. 3. Ocular tolerance especially of silicone tubings has been investigated by animal experiments. Excellent tolerance of silicone intraocularly as well as subconjunctivally has been found. This fact confirms experimental investigations by other authors. 4. In animal experiments for the first time a surgical technique securing firm anchorage of a sole silicone tubing could be developed. Insertion of a silicone catheter was combined with thermal sclerostomy; ocular hypotony was not encountered. 5. A study exploring aqueous egress following the new surgical procedure has been conducted by means of injection of fluorescein into the anterior chamber. Various exit-sites of aqueous were recorded: diffuse outflow through the filtration cleft as well as the catheter lumen, and also via channels either within lymph vessels or secondary aqueous veins. 6. Aqueous outflow following the seton operation has also been studied by scintigraphic means; the first description of this method in glaucoma-operated eyes is presented. Applying this technique not only the existence of a filtering bleb is documented, but in addition the speed of aqueous transit through the filtering bleb was measured. This transit has been found to be a rapid one. 7. The clinical results of this type of seton operation do confirm the experimental evidence of excellent ocular tolerance of silicone tubings as well as the reliability of their firm anchorage. Postoperative tension with or without additional antiglaucomatous medication proved quite satisfactory. 8. The proposed surgical procedure is recommendable especially in patients exhibiting haemorrhagic glaucoma, were conventional methods are likely to fail in the majority of cases.

Adult↗
PubMed1979

[Aqueous outflow following seton operations (author's transl)].

In 6 rabbits which had been submitted to a seton operation 2--6 months previously, the mode of aqueous outflow has been documented photographically after injection of fluorescein into the anterior chamber. In all 6 cases the catheter allowed direct passage of aqueous humour through its lumen into the subconjunctival space; further sources of diffuse aqueous egress were provable at the site of the corneo-slceral wound, either next to the catheter or aside from it. Additional drainage via preformed channels occurred through lymphatic vessels as well as through secondary aqueous veins.

Animals↗
PubMed1979

[Fluorescence-angiography, infrared-photography and histology in malignant melanoma of the papilla (author's transl)].

In a 60-year-old female a juxtapapillary malignant melanoma of the choroid invading and strangling the prelaminary section of the optic nerve head, and being masked by a massive papilledema, could be revealed by combined application of ultrasonography, fluorescenceangiography and infrared-photography. The histological examination confirmed the clinical diagnosis.

Cranial Nerve Neoplasms↗
PubMed1979

[Clinical experience in glaucoma surgery utilizing silicon catheters (author's transl)].

In 7 probands exhibiting haemorrhagic glaucoma a combined thermosclerostomy with insertion of a silicons tubing (with or without basal iridectomy) has been performed. The catheter had an inner diameter of 0,5 mm, measuring about 5 mm in length and projecting about 1,5 mm into the anterior chamber. The tubing has been anchored proximally with two nylon sutures (10--0) to the corneal wound edge going through full thickness cornea; the distal end has been anchored with two more nylon sutures to underlying sclera. Tenon's capsules and conjunctiva were closed separately. In all cases the tubing has been well tolerated and did not exhibit any sign of displacement, the intracameral opening remained patent. During an observation period of 3--16 months with or without additional antiglaucomatous medication an intraocular pressure between 14--22 mm Hg could be achieved; all patients remained asymptomatic.

Adult↗