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Biomedical subjects

I F Herrmann

Publications and source records attributed to I F Herrmann.

31 records · Page 2Linked to original sources
PubMed1978

[The value of fine-needle-cytology, imprint-cytology and histology in the head-neck-region (author's transl)].

Comparative studies about the fine-needle-cytology, imprint-cytology and histology furnished an almost complete agreement between imprint-cytology and histology. Suspected tumor findings by way of fine-needle-biopsy deserve the same place as similar histological examinations. Negative cytological results have to be critically evaluated. Fine-needle-cytology presents a quick and not too painful procedure that is both relatively free of complications and repeatable examination.

Cytological Techniques↗
PubMedDate not supplied

Head and neck carcinoma models. In vivo reproduction in athymic mice and in vitro culture.

683 tumour fragments from 63 head and neck carcinoma patients were cultured in vitro. Two laryngeal carcinomas and two salivary gland carcinomas were established into permanent cell lines. Malignancy of these cultured cells was proved by cloning, by chromosomal analysis and by transplantation into athymic (nu/nu) mice. Experiments demonstrating preservation of histological, biochemical and antigenic properties in the tumour models counter the objection that tumour-specific characteristics may be lost.

Animals↗
PubMedDate not supplied

Experiments in surgical voice restoration using valve prostheses.

As our experience with 132 laryngectomees shows, the quality of tracheopharyngeal speech differs. Effortless tracheo-pharyngeal speech requires low flow resistance. Testing the individual factors that influence flow resistance and which are due to the prosthesis, we found that prosthesis diameter and slit length were most important. Various types of valve prosthesis differ considerably in their flow resistance. However, a low-flow resistance valve prosthesis is only partly responsible for easy phonation: Contact between the pharyngeal end of the prosthesis and surrounding tissue may influence voice quality considerably. A later paper will describe the extent to which surgery can create a low-resistance vibratile upper digestive tract.

Humans↗