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Biomedical subjects

I F Keymer

Publications and source records attributed to I F Keymer.

At least 37 records · Page 2Linked to original sources
PubMed1976

Mucosal herniations in the colons of non-human primates.

Herniations of the mucosa through the colonic muscularis mucosae are described in apes and monkeys suffering from inflammatory disease of the colon as well as in apparently normal animals. Submucosal lymphoid nodules, causing discontinuity or splaying of the overlying muscularis mucosae were seen in profusion in normal colons. Evidence pointed to the fully developed herniations evolving therefrom by means of extrusion of the mucosa and that such extrusion resulted from or was hastened by contraction or hypertonicity of the colonic musculature.

Animals↗
PubMed1975

Ulcerative colitis in apes: A comparison with the human disease.

The pathological changes in the colons of two young gorillas and an adult orang-utan which developed diarrhoea and died, are described. Since no causative agents could be identified and the changes were indistinguishable from the active phase of ulcerative colitis in humans, these cases were considered examples of this disease in apes. Evidence of early healing was found in one case and the suitability of apes and monkeys as possible animal models of the human disease is discussed.

Animals↗
PubMed1975

The pathology of measles in Abyssinian Colobus monkeys (Colobus guereza): a description of an outbreak.

The pathological changes found in four Abyssinian Colobus monkeys (Colobus guereza) dying of measles are described. Warthin-Finkeldey giant cells were plentiful in the lymphoid tissue and spleen, in the mucosa of the alimentary tract and in the lungs, where they accompanied a non-suppurative pneumonia. In the alimentary tract they were most frequent in the colon when an associated colitis was present. Measles virus was recovered from the lung tissue of one animal, the virus being neutralised by both human and rhesus monkey anti-sera. This together with the close similarity between the pathological changes in human and monkey measles, supports the contention that the two diseases are one and due to the same virus.

Animals↗