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Biomedical subjects

I F Russell

Publications and source records attributed to I F Russell.

8 recordsLinked to original sources
PubMed1992

Spinal anaesthesia for caesarean section: 0.125% plain bupivacaine 12 ml compared with 0.5% plain bupivacaine 3 ml.

Forty women had elective Caesarean section under spinal anaesthesia with either 0.5% bupivacaine 3 ml or 0.125% bupivacaine 12 ml, injected at a rate of 1 ml/5 s. For 30 min after the spinal injection, each patient lay on her right side. Compared with the patients given 3 ml, in those given bupivacaine 12 ml there was a significantly greater spread of block (P less than 0.02 for analgesia; P less than 0.002 for touch) and significantly less variation in levels of block (P less than 0.02 for analgesia; P less than 0.04 for touch). However, within 5 min of placing the women in a supine, tilted (right hip up) position, there were no clinically or statistically significant differences in the levels of block between the two groups.

Adult↗
PubMed1979

Ketamine and agenesis of the corpus callosum.

Ketamine did not provide adequate anaesthesia for pneumoencephalography in a 10-week-old child with agenesis of the corpus collosum. Associated neurological defects are the most likely reason for this failure.

Agenesis of Corpus Callosum↗
PubMedDate not supplied

Spinal anesthesia for cesarean delivery with dilute solutions of plain bupivacaine: the relationship between infused volume and spread.

In a prospective open study, 40 women received spinal anesthesia for cesarean delivery induced with 15 mg glucose-free bupivacaine administered in dilutions of 0.5% (3 ml), 0.25% (6 ml), 0.125% (12 ml) and 0.083% (18 ml). The solutions were infused over 30 minutes while the women lay in the right lateral decubitus. No clinical or statistical difference in the final level of block was observed between the groups. All the solutions behaved as if slightly hypobaric with the development of essentially unilateral blocks during the infusion period. At the end of the infusion period when the women were turned from the lateral decubitus to a supine tilted position, there was a sudden rise in the levels of block on both sides of the body such that, by ten minutes after turning, there was no discernible difference between the two sides. The final block levels attained were within the expected range for conventional spinal anesthesia using 2.5-3.0-ml glucose-free 0.5% bupivacaine. The findings suggest that the subarachnoid spread of isobaric/hypobaric spinal anesthetic drugs is a complex process unlikely to be explained by reference to simple models of the spinal curves.

Adult↗