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Biomedical subjects

I F Vil-Vilyams

Publications and source records attributed to I F Vil-Vilyams.

8 recordsLinked to original sources
PubMed2000

Muscle derived serum enzyme accumulation after +Gz acceleration test in Rhesus monkeys exposed to bed rest.

It is known that several hours of intensive muscle tension result in accumulation of muscle derived enzymes and structural proteins (see review by Clarkson, 1997). We have assumed that, firstly, acute exposure to hypergravity may induce accumulation of serum creatine phosphokinase (CPK), and, secondly, level of that accumulation may be considerably altered after long term hypokinesia.

Animals↗
PubMed1982

Human adaptation to simulated gravitational fields.

We present the resuIts of manned studies in which test subjects were exposed to simulated zero g (water immersion or head-down tilt at -6 degrees) and head-to-feet acceleration. The findings give evidence that humans have different individual tolerances to an acceleration of +3 Gz after exposure to zero g, whether simulated by immersion or by head-down tilt. The paper discusses the role of functional relationship between water balance and cardiac output in the establishment of adaptive reactions to simulated zero g.

Acceleration↗
PubMed1981

Human adaptation to simulated gravitational fields.

We present the results of manned studies in which test subjects were exposed to simulated zero g (water immersion or head-down tilt at -6 degrees) and head-to-feet acceleration. The findings give evidence that humans have different individual tolerances to an acceleration of +3 Gz after exposure to zero g, whether simulated by immersion or by head-down tilt. The paper discusses the functional relationship between water balance and cardiac output in the establishment of adaptive reactions to simulated zero g.

Adaptation, Physiological↗
PubMed1979

Prophylactic [correction of prophylatic] effects of intermittent acceleration against physiological deconditioning in simulated weightlessness.

The prophylactic effect on adult human males of intermittent acceleration against physiological deconditioning in weightlessness simulated by water immersion was studied at +0.8, +1.2, and +1.6 g. These prophylactic exposures reduced renal excretion of fluid and plasma volume changes, and increased venous compliance and the time at which the subjects could tolerate an acceleration field of +3 g.

Acceleration↗
PubMed1977

Prevention of human deconditioning during prolonged immersion in water.

A 56-day immersion experiment in which two subjects participated was carried out. During the experiment the preventive effect of periodic acceleration combined with exercise and water-salt intake was assessed. Simulating an increased gravitational field, exposure to acceleration increased the static component of the load upon the musculo-skeletal system, increased the gradient of the blood hydrostatic pressure, activated mechanisms responsible for the venous return to the heart, stimulated systems regulating antidiuretic and antisodiumdiuretic reflexes. Involvement of these mechanisms restored haemodynamic parameters, fluid-electrolyte balance and blood coagulability. The prophylactic effect of acceleration was enhanced if combined with exercise and supplemented water-salt intake.

Acceleration↗
PubMed1976

Deconditioning during prolonged immersion and possible countermeasures.

Test subjects covered with a waterproof highly elastic cloth were exposed to 13-day water immersion up to the neck. They were divided into two groups. The first (control) group consisting of six persons was exposed to immersion alone and the second (experimental) group was exposed daily to accelerations of 0.6-2 Gz for 60-90 min during the last 6 days of immersion. Before and after immersion all the test subjects were exposed to +3 Gz for 5 min which served as a provocative test. These experiments give evidence that the use of dry immersion allows experimentation during prolonged immersion without concomitant complications. Variations in the physiological parameters (cardiovascular system, fluid-electrolyte balance, blood-coagulatory system) are indicative of the preventive effect of periodic accelerations during 13-day immersion.

Acceleration↗