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Biomedical subjects

I Fischler

Publications and source records attributed to I Fischler.

12 recordsLinked to original sources

Brain potentials related to seeing one's own name.

Subjects were assigned an assumed name and then shown a series of statements of the form, "My name / is / X", where X was the assumed name, their own first name, or one of a set of other false names. Their task was to respond positively to the "assumed" name and reject as false all other names, including their own. An N380 feature of the averaged task-related brain potentials, considered to be inversely related to the degree of contextual priming, was greatly enhanced for the false names compared to the assumed name. The N380 to one's own name was more similar to that of the false than the assumed name, indicating that the sentence context's priming of various names was under the subjects' attentional control, and that the late negativity could be modulated by this attention. In contrast, a large P510 feature distinguished one's own name from the false name, and this difference was unaffected by practice. Even in cases, then, where the context allows anticipation of one verbal event (here, the assumed name), a highly overlearned and salient stimulus such as one's own name continues to produce a distinctive neural response.

Adolescent↗

Brain potentials during sentence verification: automatic aspects of comprehension.

College students learned a set of facts relating fictitious people and their occupations (e.g. 'Matthew is a lawyer'). Event-related brain potentials (ERPs) were recorded while they subsequently viewed a series of such statements presented in segments (e.g. 'Matthew/is a/dentist'). ERPs to occupations completing statements falsely were significantly more negative than those to true statements in an interval 200-420 msec poststimulus (peak N320), whether subjects were required to make a decision about each statement or passively view the presented segments (Experiments 1 and 2). A later ERP positivity was observed during 'response' trials that was of longer latency for false than true completions; but this positive component was greatly attenuated during 'no-response' trials. The enhanced N320 for false completions was not affected by requiring subjects on some trials to respond incorrectly (Experiment 3). It is concluded that attending to a presented word results in an automatic analysis of its meaning in the context of a preceding verbal input, and that ERPs can indicate the nature of the output of that analysis.

Brain↗

Brain potentials during sentence verification: late negativity and long-term memory strength.

Subjects decided whether self-referential statements were true or false. Event-related potentials (ERPs) associated with final words creating false statements displayed a late negativity (N340) relative to ERPs for true completions. The size of this difference between true and false statements was greater for highly familiar statements (e.g. "My name is Ira") than for less familiar ones (e.g. "I go to bed late") even after all the statements had been practised a number of times. The late negativity appears to be associated with a discrepancy between presented and remembered information, and its magnitude reflects the long-term familiarity or strength of the remembered information.

Adult↗