[Appendicitis--change in the disease picture?].
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Appendectomy↗
Biomedical subjects
I Franz
Publications and source records attributed to I Franz.
[Acute appendicitis].
The appendectomy rate in the Federal Republic of Germany has decreased considerably over the past 20 years; in Hannover it has declined by 50%. The number of patients not undergoing operations after hospitalization has increased from 20% to about 65%. Mortality has decreased by 80%, now reaching 0.7 for 100,000 of the population. More than 80% of the deceased are over 65 years old. The main cause of death is advanced appendicitis including perforation. In the North German Patient Appeal Office 10% of all complaints in general surgery concern appendicitis, mostly because of delayed diagnosis. A considerable number of appendectomies is carried out simultaneously in gynecological operations.
Acute Disease↗
[Comparative in-flight study of a scopolamine-containing membrane plaster versus dimenhydrinate under defined acceleration conditions].
The efficacy and tolerability of Scopoderm TTS (SCOTTS), a transdermal system containing scopolamine, were compared with those of the oral antiemetic dimenhydrinate (double-dummy technique) in a controlled, double-blind, within-patient study including 20 test persons with proven motion sickness. During a 1-h test flight, SCOTTS proved to be as effective as dimenhydrinate. The efficacy and tolerability of both SCOTTS and dimenhydrinate were assessed as to be equally good. Due to its galenic properties, SCOTTS is effective over a 72-h period and therefore is useful in the prevention of motion sickness during long-distance flights, where it is superior to dimenhydrinate.
Acceleration↗