I G Blair | PubMed Health

PubMed1992

Paediatric myelography with iohexol.

32 paediatric patients requiring myelography were studied with iohexol 210 mgI/ml (n = 15) and iohexol 180 mgI/ml (n = 17). Visualization was good or excellent in over 90% of the group receiving the higher concentration and in over 83% of the lower. There were no side effects in either group and vital signs were not significantly altered during the procedure. In the majority of patients (14/18) who had CT, additional diagnostic information was obtained. Iohexol 180 mgI/ml is preferred for routine use, but 210 mgI/ml may give superior visualization with no apparent added risk. Procedural technique and good communication with the patients and their families may have contributed to the absence of side effects.

Child↗

PubMed1990

Adult myelography with iohexol.

An open, multicenter trial of adult myelography was carried out at six centers in 117 patients with iohexol (Omnipaque) 240 mg I/ml and 300 mg I/ml to determine whether there was a difference in visualization or side-effects when a lumbar or cervical approach was used to visualize the areas where disease was suspected. One hundred and thirteen myelograms were analysable. In over 85% of the myelograms with a lumbar approach, visualization of the area injected was excellent or good. Just over half of these were obtained with the intention of visualizing primarily the cervical area, and in 93% of these visualization was good or excellent at that site. In 100% of the cervically injected myelograms, visualization was excellent in the cervical area. Areas more distant from the injections were well visualized in the majority of patients. There was no significant difference overall in visualization with either of the two concentrations of iohexol used. There were 59 side-effects, mostly mild in nature; 40 of them occurred in 50 patients receiving the higher concentration and 19 in 63 patients receiving the lower concentration. The most common side-effect was headache (23 patients). Nystagmus was the only severe side-effect and occurred in only one patient having cervical myelography. The patient made a complete recovery within 36 hours.

Blood Chemical Analysis↗