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Biomedical subjects

I G Mikhaĭlov

Publications and source records attributed to I G Mikhaĭlov.

At least 19 recordsLinked to original sources
PubMed2000

[Special features of actual nutrition and nutritional status of children living in the Yamal-Nenets Autonomous District].

Actual nutrition of children living at boarding-school of the Yamal-Nenets autonomous district and also characteristics of their health, such as capacity for work, vitamin metabolism, physical development and activity of bio-oxidant systems of organism have been studied. The obtained results have become the basis for developing scientifically substantiated principles of creating balanced nutrition ration with antioxidant properties for the children living at the Far North.

Child↗
PubMed2000

[A comparative evaluation of treatment methods for a genital papillomavirus infection in women with different viral genotypes].

Such genotypes of human papilloma virus (HPV) as "malignant" (180), "benign" (49) and indeterminate (127) were identified in 356 females by PCR and cytological procedures. The following therapeutic techniques were compared: cryodestruction of the uterine cervix (60), antiviral medication (AVM) (19), combination of AVM and cryodestruction (224), and combination of AVM and laser destruction (54). In the "malignant" HPV group, AVM in conjunction with cryo- or laser destruction was significantly more effective than cryodestruction or AVM alone. Both cryodestruction alone and in combination with AVM were more effective in treating "benign" genotypes. Repeat courses showed the same tendency.

Acridines↗
PubMed1999

[Surgical treatment of chronic post-traumatic osteomyelitis of the femur in pseudarthrosis, ununited fractures and defects].

The authors have analyzed the results of treatment for chronic posttraumatic osteomyelitis of the femoral bone in 69 cases of ununited fractures, false joints ad femoral bone defects. The treatment included surgical sanation of the osteomyelitic nidus together with aspiration lavage drainage and extranidal osteosynthesis by external fixation as well as local and general antibacterial therapy. In 13 cases free bone autoplasty of the osteomyelitic cavities or defects was used together with spongious structures of iliac bone (crest and wing), in 2 of these patients it was applied for replacement of the large defects of the diaphysis of the femoral bone (8 and 12 cm). In 57 patients surgical treatment was carried out in one stage, a major requisite for this was the opportunity for joining bone fragments inside the open wound after sequestrectomy as well as stable external fixation by the apparatus. This treatment gave successful results in 97% of patients.

Adolescent↗
PubMed1989

[Surgical treatment of ununited fractures and pseudarthroses of the femoral diaphysis].

The article analyses experience in the treatment of 125 patients with ununited fractures and pseudarthrosis of the humeral diaphysis by osteosynthesis with massive compressing metal plates. The possibility of creating the necessary reserve of mechanical stability at the expense of the massive plates and strained fixation allows immobilization in a plaster cast to be avoided in most cases and early motor rehabilitation of the patients to be undertaken. The results were positive in 96.8% of cases, which makes it possible to consider the method to be sufficiently effective in the management of fractures of the humeral diaphysis and their sequelae.

Adult↗
PubMed1986

[Electron microscopic characteristics of oncocytoma of the lung, small intestine and adrenal gland].

Electron microscopic characteristic of 3 oncocytomas (of lung, small intestine, adrenal) is presented. All the tumours had a similar ultrastructure with a large number of mitochondria in their cytoplasm. The electron microscopic study confirmed the diagnosis of oncocytoma in 2 cases. In one case the diagnosis of oncocytoma was made on the basis of the electron microscopic examination.

Adenoma↗
PubMed1981

[Pigmented neuroectodermal tumor (melanoameloblastoma)].

A pigmented tumor (melanoameloblastoma) in a 4-month-old infant localized in the upper jaw is described. The tumor consisted of cells with melanin granules in the cytoplasm. The detected neurosecretory granules and melanosomes in the parenchymal cells of the tumor suggest to be of neuroectodermal origin.

Child, Preschool↗
PubMed1981

[Ultrastructural characteristics of the cells of human medullary thyroid cancer].

Eight medullary carcinomas of the human thyroid gland were examined electron microscopically for identification of cell types forming these tumors. The diagnosis was based on classical histological criteria including a positive reaction for amyloid and impregnation according to the method of De Grandi specific for C-cells. The human medullary carcinoma of the thyroid gland was found to contain dark, light, and intermediate tumor cells. The ultrastructural features of these types of cells suggest that they may be regarded as being at different stages of the intensity of synthesis processes more in the light cells. Amyloid production in this type of cancer is associated with tumor cells.

Carcinoma↗
PubMed1980

[Comparative quantitative electron-microscopic study of the nucleoli of human thyroid oncocytes and follicular cells].

The qualitative and quantitative ultrastructural examinations of nucleoli of follicular cells and oncocytes of human thyroid revealed no morphological differences between these two types of cells and confirmed the presence of all structures necessary for normal functioning. Oncocyte nuclei are not carriers of morphological alterations which could have indicated severe functional disorders in these cells, and morphological and morphometric examinations indicated functional intactness of nuclei and nucleoli.

Adenoma↗
PubMed1980

[Electron microscopic diagnosis of oncocytoma and renal cell carcinoma].

Electron microscopic examination of two tumors of the kidneys with similar histological structure (large eosinophilic cells with granular cytoplasm) showed that such tumors may be of different histogenesis (cytogenesis), their morphological picture in the light microscope being similar.

Adenocarcinoma↗
PubMed1975

[Study of some oxidoreductases in nerve tissue culture].

A change in the activity of succinic dehydrogenase, of the NAD- and NADP-diaphorases was studied in the dissociated culture of the cerebellum of neonatal rats under the effect of immune serum of the animals with an experimental allergic pertussis encephalomyelitis. There was revealed an increase in the activity of oligodendrocytes following a 3-hour exposure with the immune serum and a reduction of the activity of the enzymes under study in the same cells after a 12-hour exposure of the cultures with the serum. In difference from oligodendrocytes, the astrocytes displayed a high activity of all the enzymes under study after a 12-hour exposure.

Animals↗
PubMedDate not supplied

[Evaluation of the dynamic ratio of Escherichia coli cell loss from the coefficient of ultrasound relaxation in a suspension].

A method for measuring the microbial cell dynamic loss modulus has been developed. The acoustic wave relaxation coefficient in the suspension of Escherichia coli cells was measured in relation to ultra-sound frequency and cell concentration. Using these data and proceeding from the ideas on acoustic and viscous properties of suspensions the volume dynamic loss modulus of cells was calculated. The obtained results were compared with the data on the loss modulus of albumin globules aggregates.

Escherichia coli↗