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Biomedical subjects

I G Popescu

Publications and source records attributed to I G Popescu.

50 records · Page 3Linked to original sources

Investigation on atmospheric pollen in a plain zone of Romania.

In May-August 1982 and April-August 1983 quantitative and qualitative studies on the atmospheric pollen were carried out in the town of C. using Durham's method. The number of total atmospheric pollen granules was found to exceed 1,200/sq. cm in May and 1,100/sq. cm in June. The pollen of trees (Corylus, Quercus, etc.) and the pollen of poaceous plants, the main allergogenic pollen, were found to predominate in the first part of the period and the pollen of poaceous plants (Gramineae) in the rest of the pollination season. The authors consider that the pollen of Compositae can have a certain allergogenic importance in August.

Air Pollutants↗

[Acarids of pathological significance in urine].

The present paper reports on 7 cases of primary infections, pyelonephritis and pyelocystitis, in which acrids were found in the urine during acute attacks. The cases were detected in the clinical laboratory of a county Hospital. All the 7 patients, ranging in age from 6 to 60 years, exhibited characteristic symptoms of pyelonephritis and pyelocystitis. Numerous acarids were found in the urinary sediment and, in some cases, also their eggs. Some of the acarids were motile, others were encrusted with salts. A female acarid was detected while laying eggs. In 6 patients the acardis were found in the urine only at the first examination and disappeared following the of urinary infection; in the seventh case they were detected at three consecutive examinations performed at 3--6 days interval.

Acari↗

Drug allergy: incidence in terms of age and some drug allergens.

The authors studied the incidence of drug allergy in 3 groups of subjects. In the first group the incidence was established in terms of the subjects' age: 1.8% in children up to 14 years old (323 subjects), 5.8% in middle-aged subjects (389 subjects) and 2.9% in the elderly (243 subjects). In the second partly selected group, drug allergy was studied in patients admitted to the 3rd Medical Clinic--Craiova between 2 Jan. 1981 and 31 Dec. 1982; 103 of the 8,760 patients admitted presented allergic reactions, a relatively high incidence rate (1.01%) as compared to other published reports. The third group of previously selected cases consisted of 197 patients who had come to the allergology service with complaints of present or past sensitivity to drugs. The total number of patients was 336 selected or preselected from about 10,000 subjects, to which 17 patients with a diagnosis of "asthmatic triad" must be added. Drug allergy in terms of the drug used was dominated by penicillin, pyramidon-algocalmin, aspirin, iodine preparations, etc.; foremost among the clinical syndrome were the dermatologic syndromes types I, III and IV; syndromes of the "anaphylactic shock" type, "serum sickeness" bronchial asthma, angioneurotic oedema.

Adolescent↗

Treatment of bronchial asthma with disodium cromoglycate. Special indications.

Forty patients with various types of bronchial asthma were treated with disodium cromoglycate (DSCG) for various periods of time ranging from 30 days to 90 months. The drug was inhaled through a spinhaler at 8-hour intervals. The symptoms of asthma, the respiratory function and the drug-induced reactions were checked during treatment. DSCG was salutary in about 80% of the patients with extrinsic asthma (even in those with pollen allergy diagnosed within the pollination period). The drug was also effective in patients with exercise induced asthma, asthma associated with pregnancy, asthma with adrenocorticosteroid psychosis. The patients with meal allergy (bakers and millers) treated with DSCG were able to keep their occupational activities. The drug may be used in the intrinsic asthma only in subjects with many positive skin tests and hypereosinophilia.

Adolescent↗

Investigations upon the incidence of atmospheric fungi in the town of Craiova.

The present investigation was suggested by the fact that bronchial asthma (of all types) presents in Craiova and the district of Dolj a relatively increased incidence which may be correlated with certain findings concerning the incidence of atmospheric fungi in the houses and working places of asthmatic subjects. Petri dishes with Czapek medium were exposed monthly in the open air, in 17 houses of asthmatic subjects and in a large bakery unit. The prevalence of various types of fungi was observed on the culture media and a correlation could be made with the seasons. In the houses of asthmatics Penicillium was found to predominate and in certain months of the year Aspergillus as well, which may have a certain etiopathogenic role in bronchial asthma. In certain months Cladosporium and Alternaria also appeared. In the open air the number of colonies was smaller but the incidence was identical. In the bakery unit Penicillium was predominant in 3 out of 5 months, Aspergillus prevailling in all the other months of the year. Cladosporium and Alternaria were also rather frequent. Other fungi sometimes found in relatively large proportions (Mucor, Rhizopus, Verticillium) were not in themselves etiopathogenically involved in bronchial asthma.

Air Microbiology↗

Atopic and non-atopic sensitivity in a large bakery.

Flour is an allergen which can sensitize either by the digestive or the inhalatory route, particularly those who work with this product. Factors involved occupational four-induced asthma also include various insects and their excreta, fungi and dermato-farinae. In this study, 1303 subjects from a number of bakeries were studied. They underwent allergological investigation by means of prick-tests with allergens and respiratory function tests for those with bronchial asthma. Also studied is the relationship with atopic syndromes or atopic family history.

Allergens↗

New studies on the mold spore incidence in the homes of asthmatics.

The incidence of mould spores was studied during 11 months using Petri plates with Czapek medium exposed once a month in 17 homes of asthmatics in the town, "C", situated in an agro-industrial region. Penicullium was the prevalent mould in all season; Aspergillus was dominant in February-September; Cladosporium was found in May and September; Alternaria was absent. It is assumed that some of the asthmatics in this area could have a type III hypersensitivity (asthma with precipitins).

Allergens↗

Study of the incidence and prevalence of children bronchial asthma in a Romanian town.

The incidence of bronchial asthma was investigated in a population of 4,486 schoolchildren aged 6 to 14 years from Rîmnicu Vîlcea, a Romanian town in the meridional sub-Carpathian zone of the country. The incidence of "probable asthma" was found to be 2.45% and that of confirmed asthma 1.62%. These percentages are among the highest ever encountered in Romania, in both children and adults. A family history of atopy was observed in 42.3% of the children and of asthma in 28.7%. Such big figures have never been found in adults in Romania.

Adolescent↗