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Biomedical subjects

I G Zachary

Publications and source records attributed to I G Zachary.

4 recordsLinked to original sources
PubMed1976

Further observations on the diagnosis cause, and treatment of endophthalmitis.

In our study of 54 suspected cases of endophthalmitis, vitreous aspiration was more sensitive in making a culture-proven diagnosis than anterior chamber paracentesis; Staphylococcus epidermidis was a more common cause of endophthalmitis than previously appreciated; and intraocular antibiotics in the recommended dosage are reasonably safe clinically and add a new dimension to the treatment of endophthalmitis.

Anterior Chamber↗
PubMed1976

Experimental intravitreal gentamicin.

Rabbits received intravitreal injections of gentamicin and indirect ophthalmoscopy, electroretinography, and histopathology determined relative toxicity. An intravitreal dose of 0.1 to 0.2 mg of commercially available gentamicin was well tolerated in the rabbit eye. A dosage of 0.4 mg or higher consistently produced significant ocular toxicity as evidenced by extinction of the electroretinogram, gross fundus changes, and histopathologic alterations.

Animals↗
PubMed1975

Further observations on the diagnosis, etiology, and treatment of endophthalmitis.

This report of 54 suspected cases of endophthalmitis emphasizes the following findings: 1. That vitreous aspiration is more sensitive in making a culture proven diagnosis than anterior chamber paracentesis. 2. That Staphylococcus epidermidis is a much more common cause of endophthalmitis than previously apprediated. 3. That intraocular antibiotics in the recommended dosage, are reasonably safe clinically and add a new dimension to the treatment of endophthalmitis.

Anterior Chamber↗