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Biomedical subjects

I Geller

Publications and source records attributed to I Geller.

At least 55 records · Page 3Linked to original sources
PubMed1972

Synergy of ethanol and putative neurotransmitters: glycine and serine.

The putative neurotransmitters, glycine and serine, significantly enhanced the sleeping time (loss of the righting reflex) that was induced by ethanol in mice. The observed synergistic effect between ethanol and the amino acids is probably not related to an alteration of ethanol metabolism, but rather to an interaction of these compounds in the central nervous system.

Animals↗
PubMed1971

Ethanol preference in the rat as a function of photoperiod.

Ethanol-drinking was induced in laboratory rats that were maintained in total darkness. The established preference for ethanol was not reversed under conditions of constant illumination although a decrease in ethanol intake occurred. Administration of melatonin to rats maintained under "normal" photoperiods (9 hours of darkness during a 24-hour day) also induced ethanol-drinking.

Alcohol Drinking↗
PubMed1971

Interaction effects of ethanol and pyrazole in laboratory rodents.

1. Interactions of pyrazole and ethanol were studied in three laboratory test procedures. They included sleeping time in mice, rotor rod balance in rats and lever pressing behaviour of rats.2. Equimolar concentrations of pyrazole and 3-methylpyrazole were compared for effects on enhancement of ethanol's activity on rotor rod holding time of rats.3. Minimally effective doses of pyrazole, the LADH inhibitor, and 3-methylpyrazole, a non-inhibitor of LADH, when administered before ethanol, resulted in an increased behavioural depression. These interaction effects are probably not caused by inhibition of LADH but rather by an increase in the direct depressant action of either one or both of the compounds.

Alcohol Oxidoreductases↗