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PubMed1986

Langerhans' cell population studies with OKT6 and HLA-DR monoclonal antibodies in vitiligo patients treated with oral phenylalanine loading and UVA irradiation.

In vitiligo patients, treated with oral phenylalanine loading combined with UVA irradiation (Phe-UVA), Langerhans' cells (LC) were counted in pigmented and depigmented skin. The LC, which were labelled with OKT6 and HLA-DR monoclonal antibodies, were expressed per linear mm epidermis. Before treatment the number of OKT6(+) cells was significantly increased in vitiliginous skin especially in the basal layer. Under treatment the number went down and was comparable to normal skin. When using HLA-DR labelling the number of LC increased in vitiliginous skin which had been treated with Phe-UVA. The influence of Phe-UVA on the shift of LC subpopulations is discussed.

Adult↗

PubMedDate not supplied

Right colonic diverticulitis: MR appearance.

BACKGROUND: We evaluated the magnetic resonance (MR) features of right colonic diverticulitis. METHODS: This prospective study was based on five patients selected from a group of 156 patients admitted to the radiology department for further evaluation because of clinically suspected appendicitis. All five patients had ultrasound (US) and MR studies, and four patients also had computed tomography (CT). RESULTS: In all five patients, right-side diverticulitis was seen as an outpouching of the right colon with associated circumferential wall thickening of the colon and surrounding inflammatory changes. CONCLUSIONS: Our results suggest that MR imaging can be useful in the diagnosis of right colonic diverticulitis. An inflamed diverticulum with adjacent colonic wall thickening and surrounding inflamed fat are characteristic MR signs. MR imaging can be a valuable alternative to CT in young or pregnant patients who have suspected appendicitis and an equivocal US result.

Adult↗