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Biomedical subjects

I Gyárfás

Publications and source records attributed to I Gyárfás.

18 recordsLinked to original sources
PubMed1986

Prediction of stable high blood pressure in adolescents.

We studied the relative importance of the initial BP and associated factors in adolescents to predict stable high BP. Out of 17,634 children aged 12-13 yrs an upper group/the upper 5% of the distribution curves for both SBP and DBP/a lower group/10% random from the remainder/were yearly followed for 4 yrs/boys: 1680, girls: 1643/. About 2/3 of children remained at the same percentile point: less than 30% and greater than or equal to 70% of SBP and half of them of DBP distribution. Significant positive tracking correlations were found both for SBP and DBP between the initial BP and follow-up BP readings in the same individual. Stepwise regression analysis showed that the SBP taken at the fourth follow-up can be explained by 29% in boys, 24% in girls on the basis of screening SBP and by 47% in boys, 42% in girls on the basis of SBP measured at the four previous examinations. Using discriminant analysis, 6-9 variables out of 18 studied could correctly allocate adolescents with stable SBP or DBP/less than 70% or greater than or equal to 70% at least 3 examinations/. Our study shows the importance of initial BP and a number of factors associated with stable high BP.

Adolescent↗
PubMed1985

Blood pressure in childhood and adolescence. Results from an international collaborative study on juvenile hypertension.

A total of 17,130 children of both sexes born in 1964 and living in Hungary, USSR, GDR and Cuba were examined in 1977. The children were grouped in upper (U) and lower (L) blood pressure groups and 3,640 children were re-examined in 1978-1981. The parents' age, smoking habits, marital status, the children's order of birth, number of siblings, and proportion of twins did not differ between U and L. The prevalence of hypertension and diabetes in the medical history of the children, and the prevalence of hypertension and stroke and diabetes in the medical history of the parents were significantly higher in U than in L. Signs of left ventricular hypertrophy and systolic murmurs, the magnitude of R and S waves in the ECG, and mean values of cardiothoracic and heart volume indices were higher in U than in L. Children in U were sexually more developed, taller, more obese (greater Quetelet's index and skinfold thickness) and less active physically. Average values of blood sugar and serum uric acid were also higher in U than in L. No difference was found between the two groups in the proportion of smokers and in mean cholesterol values. These differences between U and L were strengthened in comparison of children who showed repeatedly low (below the 30th percentile) or high (at or above the 70th, 90th and 95th percentile) readings in the SBP and DBP distribution curves. Since we did not find important differences when we related various factors to blood pressure taken on one or two separate occasions we emphasize the importance of casual blood pressure measurement in childhood.

Adolescent↗
PubMed1985

Factors associated with stable high blood pressure in adolescents.

Our aim was to study the relative importance of the factors associated with stable high blood pressure (BP) in adolescents. Out of 17 634 children born in 1964 and screened in 1977, two samples, an upper group [the upper 5% of the distribution curves for both systolic (SBP) and diastolic (DBP) blood pressures] and a lower group (a 10% random sample from the remainder), were chosen for yearly follow-up (1680 boys and 1143 girls) from 1978 to 1981. A multiple logistic function was used to analyse the factors associated with stable high SBP and DBP (with at least three different measurements of BP at or above the 95th percentile). Different sets of variables were studied. Of the boys with stable high SBP, 55% were found in the upper quintile of risk distribution when Quetelet's index was taken into consideration, 63% when Quetelet's index + age + heart rate+sexual maturation, 67% when Quetelet's index + age + heart rate + serum uric acid and 74% when Quetelet's index + age + heart rate + cardiothoracic index + heart volume index were taken into consideration. Of the girls with a stable high SBP, 68% were found in the upper quintile of risk distribution when any of the following variables was added to Quetelet's index + age + heart rate: R and S waves, serum cholesterol or post-load blood sugar. Similar but smaller effects of associated factors on DBP were observed. Our study shows that Quetelet's index and heart rate are the most important factors associated with stable high BP in adolescents.

Adolescent↗
PubMed1981

International collaborative study on juvenile hypertension. 1. Study procedures and screening data.

The study procedures and the results of blood pressure screening from 8 centres are reported. Data are also presented on age, sex, sexual maturity for girls, height, weight, Quetelet's index, smoking, and use of antihypertensive drugs for 92.1% of the 18 609 children born in 1964 in the 8 districts and surveyed in 1977. The girls who had reached sexual maturity had the highest means for blood pressure, height, weight, and Quetelet's index. The proportion of girls who had attained menarche differed geographically. Certain differences were found among the 8 centres in the variables measured, but when age-specific comparisons were made most of the differences in the variables disappeared. Nevertheless a lower systolic blood pressure and height and a higher pulse rate were observed in Havana, Cuba, than in the European cities. Using multivariate analysis, height, weight, pulse rate, age at survey, and sexual maturity together explained somewhat less than 20% and 10% of the variation of systolic and diastolic blood pressures, respectively. These screening data provide a baseline for a longitudinal study that will continue until 1982.

Adolescent↗
PubMed1979

Incidence and fatality of acute myocardial infarction in the community.

The incidence rate for acute myocardial infarction (AMI; diagnostic categories "definite AMI" + "possible AMI" + "insufficient data"), defined as number of cases per 10 000 population (20 years and older) and year, are highest in Berlin, GDR (63 for males, 42 for females), intermediate in Budapest (46/22) and lowest in Warsaw (38/21). In Budapest and Warsaw younger and middle-aged men suffer more frequently from AMI than in Berlin, while in the GDR capital AMI is more frequent in older men and women. In younger and middle-aged groups AMI occurs in women ten years later than in men. After standardization for age, the AMI incidence rates are not significantly different between Budapest and Warsaw, but are significantly higher in Berlin, particularly for older women. The standardized fatality rates of AMI (percentage of cases died within 28 days from all cases) for males were equally high for Berlin and Budapest (each about 50%), but in Warsaw significantly lower (42%). For females they are significantly highest in Berlin (69%), intermediate in Budapest (57%) and significantly lowest in Warsaw (40%). This is due mainly to an excess fatality within the oldest groups in the Berlin Register.

Adult↗