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Biomedical subjects

I Halle

Publications and source records attributed to I Halle.

12 recordsLinked to original sources
PubMed1999

Vitamin E hypervitaminosis in laying hens.

The aim of this investigation was to contribute to the problem of overdosing vitamin E. A total of 80 laying hens, divided into 5 groups, were fed diets supplemented with 0, 100, 1000, 10,000 and 20,000 mg/kg vitamin E over a period of 20 weeks within two brooding tests. Laying performance and hatching parameters were registered. All vitamin E doses did not significantly influence health and performances of hens. Vitamin E content of eggs increased from 1 to 4, 21, 46 and 51 mg per egg with vitamin E supplementation. High doses decreased oxidative stability of abdominal fat, vitamin A concentration of liver and egg yolk colour. In both tests vitamin E supplements of 10,000 and 20,000 mg/kg feed resulted in a decrease of living hatched chicken, which demonstrated an adverse effect. Further studies seem to be necessary to explain the effect.

Animal Feed↗
PubMed1999

[The effect of palm oil and safflower oil in the feed of parent fattening hens on fertility, hatchability and growth of progeny].

The aim of two experiments with broiler breeder hens was to evaluate the effect of diets containing palm butter or safflower oil (25 g and 50 g/kg feed, resp.) on fertility, hatchability and growth of progeny. Especially the incorporation of oleic and linoleic acid in egg yolk reflected the dietary fatty acid source. Eggs were collected and stored in the incubator at a hen age of 31, 40, 50, and 60 weeks. Hatched chicks were reared over 5 weeks. The number of fertile eggs (Experiment 1 and 2, 75 and 88%, resp.) differed between the experiments (P < or = 0.05). Neither embryonic mortality nor hatchability (Experiment 1 and 2, 76 and 78%, resp.) were significantly affected by fatty acid composition of yolk. No clear maternal dietary effect was recorded on chicken weight at hatching (Experiment 1 and 2, 43.3 g and 43.7 g, resp.) and at 35 days of age (Experimental 1 and 2, 1676 g and 1764 g, resp.) The fatty acid composition in the analysed egg yolk sac of chicks showed a different fatty level but corresponded to fatty acid composition of breeding eggs before incubation. According to a decreased level of docosahexaenoic acid in egg yolk due to increased incorporation of linoleic acid, the content of this fatty acid was also diminished in phospholipids of the brain of chicken on days 1 and 5 after hatching.

Animal Feed↗
PubMed1998

-Secondary cerebral stress of systemic origin in children with severe craniocerebral injuries-.

OBJECTIVE: To assess incidence of secondary brain insults of systemic origin (SBISOs) such as arterial hypotension, hypoxaemia, hypercarbia, and anaemia in severely head injured children; to assess their impact on mortality and morbidity in the short- and long-term. STUDY DESIGN: Prospective, open study covering a 24-month period. PATIENTS: Seventy-one children, under 15 years of age, admitted to a trauma centre for severe brain injury. METHOD: Analysis of SBISOs and outcome. RESULTS: Twenty-five children were admitted with SBISOs. The mortality rate was 37%. After hospitalization, 84% of the children with SBISOs vs 46% without SBISOs had severe disability (Glasgow outcome score = 1, 2 and 3). After 1 year, 20 out of the 45 children still alive were contacted. One of the four with SBISOs communicated a bad recovery. Fifteen children without SBISOs presented good recovery: GOS = 4-5, paediatric overall performance category (POPC scale) = 1-2. CONCLUSION: Hypotension was associated with significant increase in mortality (x 3.6) in children with severe head injury. The consequences were worse when anaemia was associated.

Adolescent↗
PubMed1998

Effects of veratridine on mechanical responses of human malignant hyperthermic muscle fibers.

BACKGROUND: To determine if alteration in the function of the sodium channel may in turn modify halothane-induced changes in mechanical responses of muscle bundles from patients susceptible to malignant hyperthermia (MH). METHODS: Mechanical responses of muscle bundles from 12 MH-susceptible and 20 MH non-susceptible patients were measured prior to and during administration of halothane alone and in the presence of 10 microM veratridine, an inhibitor of sodium channel inactivation. Peak tension (PT), time to peak tension (TPT), positive peak of isometric tension derivative (+dP/dtmax) were used to characterize the inotropic state. Analysis of relaxation process was performed using half relaxation time (RT 1/2) and the negative peak of isometric tension derivative (-dP/dtmax). The ratio (R) = (+dP/dtmax)/(-dP/dtmax) was used to measure the coupling between contraction and relaxation under isometric condition. RESULTS: Veratridine significantly enhanced the 0.5, 1, 2 and 3 vol% halothane-induced contracture and induced a negative inotropic effect in MH-susceptible muscle bundles. R increased by nearly 90% indicating that the combined effects were more pronounced in the relaxation phase. In MH non-susceptible muscle, veratridine did not significantly enhance the effects of halothane. CONCLUSIONS: These results on cut MH-susceptible human muscle bundles support the hypothesis that halothane-induced contracture in MH can be modified by the binding of an inhibitor of sodium channel inactivation.

Calcium↗
PubMed1997

Evaluation of the non invasive TOBEC (total body electrical conductivity) procedure for prediction of chemical components of male broilers with special consideration of dietary protein level.

TOBEC (total body electrical conductivity) measurement as a non invasive procedure for the estimation of body chemical composition was used to calculate calibration curves for the prediction of crude protein mass (CPM), crude water mass (CWM), crude ash mass (CAM) and fat-free mass (FFM) of male broiler chickens. A growth experiment with 3 protein levels (130, 230 and 330 g CP/kg diet, isoenergetic with 13.3 MJ AMEN/kg) was combined with TOBEC measurements and body chemical analysis in order to obtain the values necessary for calibration. A total of 196 TOBEC measurements and body chemical analysis were undertaken in time intervals of two days beginning with batch until day 17 of age. Different dietary protein levels resulted in marked differences in body weights and body chemical compositions but in similar TOBEC-responses for a given mass of FFM, CPM, CAM or CWM. Values for birds fed a diet with 130 g CP/kg diet tended to be more variable. Linear broken relationships were found between FFM, CPM, CAM and CWM, respectively and TOBEC values (E#). A set of different regression equations is given and yielded high proportions of variance accounted for the piece wise regression model (R2 ranged from 0.83 to 0.99). In spite of these high determinations the prediction of crude fat mass (CFM) by subtracting the FFM from the body weight resulted in most cases in weak determinations between observed and predicted CFM (R2 ranged from 0.38 to 0.86). The highest R2 was observed when the E# was expressed per unit metabolic body weight to the power of 0.67 and regressed on FFM expressed to the same power. In conclusion, FFM, CPM and CWM may be predicted reasonably well by TOBEC. However, these high determinations are not high enough to predict CFM accurately. In addition, the application of such regressions to an individual bird seems to be impossible. Assessment for groups of animals should be possible if errors of estimation, standard deviations and differences to be detected are taken into account in the calculation of the number of birds necessary for the TOBEC measurements.

Analysis of Variance↗
PubMed1993

[The protein turnover of different leghorn hybrids].

After N-balance experiments with leghorn-hens of five different genetic origins in the top laying period, the advanced laying period as well as at the end of the laying period and with feeding of soybean meal/fish meal protein, the nitrogen maintenance requirement per live weight kg0.67 was ascertained regressively by approximation of the N-balance from N-increasing experiments to an exponential function. The Net Protein Utilization (PNu) curve and the apparent Net Protein Utilization (PEW) curve could be described as utilisation values from the N-retention curve (e-function). Moreover the relation between N-intake/LW kg0.67 and egg-N-discharge/LW kg0.67 from N-balance made it possible to estimate N-retention in the body. Finally, capability of the five origins at equal protein and S-AA intake respectively were compared.

Animal Feed↗
PubMed1990

[Nutrition of the cat].

The requirement of the cat in respect to protein, energy, vitamins and minerals are presented. The special requirements of this carnivore appear to be due to the loss or charge of certain metabolic processes which are normally present in species such as the dog.

Animal Nutritional Physiological Phenomena↗
PubMed1984

[Effect of graded nitrogen supplements on egg protein synthesis and body protein retention in broiler hens].

In the top laying period (29th/30th week of life) egg protein synthesis and protein retention in the bodies of laying hens were ascertained. Based on egg-N analyses, the relation between N-intake/live weight0.67kg and egg-N discharge/kg LW0.67kg was regressively calculated and described. The subtraction of egg-N discharge/LW0.67kg from N-balance/LW0.67kg made it possible to estimate N-retention/LW0.67kg in the body. From the intersection of this curve with the chi-axis it follows that the broiler hen meets the N-requirement for maintenance and egg production with a daily consumption of 1,264.7 mg N/LW0.67kg, which corresponds to 15.8 g crude protein, and then neither loses nor retains body protein. At a daily intake of this amount of CP (15.8 g) the broiler hen produces 44.1 g egg per day. An energy intake of more than 70 EFUhen/animal and day resulted in fat retention in the broiler hen.

Animals↗
PubMed1984

[Protein utilization as well as crude protein and amino acid requirements of broiler hens].

After N-balance experiments with broiler hens in the top laying period and the feeding of soybean coarse meal/fish meal protein the protein utilisation values were calculated. The PNu curve and the PEW curve could be described as utilisation values from the N-retention curve (e-function). At an intake of N at which the hen neither decomposed nor retained protein, the utilisation (PNu) for maintenance and egg production was 55.3% and the utilisation of feed protein for egg production 49.4%. Maximum PEW 34.3% could only be ascertained at an N-intake/LW0.67kg of 1500 mg. The corresponding crude protein quota of 18.7 g recommended as crude protein requirement is calculated from this N-quota (xm) and a live weight of the broiler hen of 2804 g. For the same N-quota (xm) and the same live weight of the hens this results in a necessary quota of S-AA of 694 mg per hen and day. Provided the daily feed intake is 145 g and thus the intake of crude protein 18.7 g and that of S-AA 694 mg per hen, the necessary crude protein content of the feed is 130 g per kg original substance and an S-AA concentration which is equivalent to 3.7% of the crude protein (in g/16 g N).

Amino Acids↗
PubMed1983

[Methodological studies on determination of the digestibility of crude protein in chickens].

A comparison of various methods for the determination of the digestibility of crude protein in chickens was made. The chemical methods of dividing faeces and urine according to HARTFIEL and EKMAN were tried out, and a new method based on the determination of alpha-NH2-N was developed and tested. Colostomy of hens served as the basis of the comparison for the correctness of the chemical methods. The best approximation to the digestibility quotient of the crude protein according to colostomy was achieved with the alpha-NH2-N-method, which can to a large extent be well automated and can do without N-determination. Faeces-urine-N-separation according to EKMAN also resulted in a good approximation to the values according to colostomy.

Animals↗
PubMedDate not supplied

[Evaluation of the energy concentration of feed mixtures for poultry based on the chemical analytical data].

Based on data material available for 33 feed mixtures, several regression equations were developed which make the estimation of energy concentration (EC) on the basis of the content of crude nutrients possible. The values received from the various equations were compared with those resulting from digestibility experiments with colostomized male and female chickens. An estimation equation is recommended resulting from the regressions for the digestibility of the individual crude nutrients: EC = 0.604 X crude protein content + 2.045 X crude fat content + 0.901 X crude carbohydrate content-158.3.

Animal Feed↗