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Biomedical subjects

I Hammad

Publications and source records attributed to I Hammad.

3 recordsLinked to original sources

Marginal castability of two different materials (a comparative study).

Achieving a clinically acceptable margin is a conspicuous objective to any practicing dentist. The main concern is the space existing between the margin of the prepared tooth and that of the final restoration. Marginal fit has been measured and evaluated in a variety of methods., and a gap of approximately 50 microns is usually considered acceptable. While inlay wax is the material commonly used in the wax-up stage when fabricating crowns and bridges, Duralay (methylmethacrylate) is a material widely used nowadays in the field of fixed prosthodontics. Due to the ease of using this material intra-orally to form margins, an attempt is made to compare the castability of margins made out of inlay wax to the ones made out of Duralay.

Crowns↗

Familial pericentric inversion of chromosome 13, 46,XX,inv (13)(p13;q11): a new variant.

A 10-year-old female with right oblique inguinal hernia was investigated to exclude an XY karyotype. Chromosome analysis of peripheral blood showed 46,XX,inv(13)(p13;q11). In vitro aneuploidy was observed in two cells: a) 46,XX,inv(13), inv(13); b) 47,XX, +inv(13). Her father and three sisters were carriers for inv(13). Herein the authors review briefly familial inv(13)'s and report a new variant involving breakpoints (p13;q11).

Child↗

Mosaicism 45,X/46,X, t dic(Xp:Xp) in a girl with short stature.

An eight-year-old girl with marked short stature and no apparent stigmata of Turner syndrome was investigated. Clinical features include bilateral epicanthic folds, frontal bossing, prominent ears and normal intelligence. Ultrasound scanning revealed an apparently normal vagina, streak ovaries and no uterus. Bone age was normal. Karyotype analysis of peripheral blood lymphocytes showed mos 45,X/46,X tdic(Xp:Xp) in the ratio 66:34, respectively. In addition, three cells with different abnormal X chromosomes were present which possibly originated from a 46,XX clone. Replication of the duplicated X chromosome was consistently late and symmetrical. Buccal smear confirmation of the karyotype showed Barr body negative in 90% and large or bipartite in 10% of the cells. Karyotypes of the parents were normal. The clinical manifestations in cases of Xp deletion due to terminal rearrangement associated with or without a 45,X cell line are discussed.

Body Height↗