Biomedical subjects
Publications and source records attributed to I Holroyd.
A case of multicentric vanishing bone disease with maxillofacial involvement in a 4-year-old boy is presented. The clinical and histologic features are described along with the subsequent management of the disease, and the literature concerning this unusual and rare condition is reviewed.
The General Dental Council guidelines regarding the use of general anaesthesia in general practice have changed; inhalation sedation with nitrous oxide has been shown as a safe alternative to general anaesthesia for many patients and is a technique particularly suited to the practice environment.
We present a rare finding of adenomatoid odontogenic tumour (AOT) in a 12-year-old boy who was referred to the Department of Paediatric Dentistry at the Eastman Dental Hospital for the extraction of a carious maxillary permanent molar. First presentation revealed that the maxillary right permanent lateral incisor and canine were unerupted. Radiological examination revealed a circumscribed radiolucent area associated with the distal aspect of the maxillary right permanent lateral incisor. The patient was admitted to our Day Care Unit where the carious maxillary molar was extracted and the radiolucent area associated with the maxillary right permanent incisor was explored. Pathological examination confirmed the lesion as adenomatoid odontogenic tumour. We present a brief review of the literature and consider how differential diagnosis of this tumour from more common odontogenic lesions can be established.
A unique family is recorded in which triplets were observed with the hypomaturation type of amelogenesis imperfecta. A simple technique of DNA analysis showed that two of the more severely affected triplets were monozygotic and the third less severely affected triplet dizygotic.
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