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Biomedical subjects

I Holtby

Publications and source records attributed to I Holtby.

9 recordsLinked to original sources

Outbreak of Salmonella enteritidis phage type 4 infection associated with cheese and onion quiche.

Twelve people developed gastrointestinal symptoms suggestive of food poisoning after a party attended by between 60 and 80 people. The outbreak went unrecognised, however, until general practitioners admitted three patients to hospital, where faecal specimens were examined. An epidemiological investigation identified 12 cases, and a case control study showed a significant association between illness and eating a cheese and onion quiche at the party. Salmonella enteritidis phage type 4 was cultured from three out of seven faecal specimens obtained from cases. Consultants in communicable disease control should continue to encourage general practitioners to investigate and notify suspected cases of food poisoning.

Adult

Evaluation of pure tone audiometry and impedance screening in infant schoolchildren.

STUDY OBJECTIVE: The aims were (1) to evaluate impedance measurements against pure tone audiometry as a screening method for the detection of middle ear changes associated with hearing loss in infant school children; (2) to estimate the costs of the health authority of each method. DESIGN: The study involved two stage screening in which both methods were offered, pure tone audiometry being carried out by school nurses and impedance screening by a doctor. SETTING: 18 infant or primary schools in Langbaurgh, Cleveland, UK. PARTICIPANTS: 610 previously unscreened infant school children took part in the study. MEASUREMENTS AND MAIN RESULTS: Main outcome measures were the sensitivity, specificity, and predictive value of each screening method, using clinical assessment and action as the validating technique. The sensitivity and the predictive value of a positive test in two stage impedance screening was markedly superior to that of pure tone audiometry. The specificity was similar using the two methods. In addition the impedance methods was more rapid and estimated to consume less resource as a screening procedure than pure tone audiometry. CONCLUSIONS: The superiority of the use of impedance screening established in this study should be confirmed in a subsequent audit carried out purely by school nurses.

Acoustic Impedance Tests