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Biomedical subjects

I I Deriabin

Publications and source records attributed to I I Deriabin.

At least 19 recordsLinked to original sources

[Status of the blood coagulation system in traumatic disease].

Under examination there were 198 patients with severe mechanical traumas at their admission to the clinic and on the 1st, 3d, 7th, 14th and 21st days by 25 hemocoagulation parameters determined by common present-day methods. The direction and degree of hemocoagulation alterations were found to be related with the severity of trauma, blood loss volume and severity of shock. It was shown that disseminated intravascular coagulation (DIC) of the II and III degree was developing in critical associated traumas, massive blood loss and severe shock in acute period of the disease. The acute form of DIC with reactive fibrinolysis was established in the lethal outcome during the shock period, latent (slow) DIC with local fibrinolysis took place in lethal outcomes in later periods.

Adolescent

[Indications, methods and results of amputations of the extremities in isolated, multiple and associated traumas].

An analysis of 246 observations has shown that in patients with crushed extremities accompanied by shock the amputation is the most important antishock measure. The amputation performed by the method of primary surgical treatment of the wound is the method of choice. The amount of postoperative complications can be considerably reduced by using the primarily delayed suture, carbon sorbents on the stump wound, temporary immobilization of the extremity stump.

Adult

[Characteristics of the pathogenesis of suppurative-septic complications of severe trauma].

The article analyzes results of examination of 261 patients with severe mechanical injuries. The examinations were performed at different periods after the trauma by biochemical and immunological methods. It was established that a number of indices (content of blood glucose, activity of aspartate aminotransferase, alanine aminotranspherase and T-lymphocyte content) were reliably different depending on the clinical course and the outcome of the trauma disease.

Adolescent

[Potentials of infusion therapy in enhancing the detoxification effect of hemosorption in patients suffering from suppurative-septic complications of mechanical injury].

Under study was the application of microvasoplegia as a method of preoperative management in fulfilling hemosorption in patients with pyo-septic complications of a severe mechanical trauma. The method of infusion and medicamentous therapy used before hemosorption is described. Laboratory examinations of the enzyme toxemia level have shown pathogenetic grounds of the complex method of treatment. Positive clinical results were obtained.

Anti-Bacterial Agents

[Immunological status and somatotropic activity of the pituitary in combined abdominal injuries complicated by peritonitis].

Associated injuries of the abdomen result in peritonitis twice more often than isolated ones, the peritonitis having more severe course and being the cause of lethal outcomes in 57% of the victims. The immune deficient state is thought to be one of the causes responsible for the reduced resistance to infection and the development of peritonitis in the postshock period. Patients with associated traumas show a considerable inhibition of the immune system within several hours and an impairment of its regulation which grows during the next day. So, even at the early terms the operative methods must be similar to those used in operations for the developed peritonitis.

Abdominal Injuries

[Dependence of the effectiveness of massive blood transfusions on the state of cellular and humoral immunity in severe mechanical injury].

The observation of 97 patients with severe mechanical traumas has shown massive hemotransfusions performed within the first two days subsequent to trauma against the background of maximum reduced cell immunity to be much more efficient than the massive hemotransfusion performed within the 3d--7th days after trauma (against the background of repairing cell immunity).

Acute Disease

[Respiration disorders after severe mechanical trauma].

The external respiration has been studied in 221 patients. The disorders in pulmonary gas exchange subsequent to an injury are due to decreased ventilation volumes, delayed diffusion of inhaled gases and disturbed blood circulation in the lungs. Functional disorders are often aggravated by pulmonary complications.

Adult

[Characteristics of the clinical course and treatment of trauma to various areas of the body combined with facial and jaw injury].

The cases with combined maxillofacial injuries and traumas of other localization should be considered as cases of a higher risk of septic complications. The specialized stomatologic acid ought to be rendered to such cases with the nearest post-shock period, not later then within 36 hours after trauma. The analysis of 291 clinical observations is set forth.

Accidents

[Diagnostic laparocentesis in closed abdominal injury].

To improve the diagnosis of closed abdominal trauma since 1966 the authors have been widely employing laparocentesis. The results of using abdominal punctures an 260 patients are reported. The method proved to be reliable in 97.7%. The use of laparocentesis enabled the authors to reduce the number of errors by 7.3 times, to shorten the terms of establishing the diagnosis by 4 times as compared with the control group of patients (190 subjects in whom the recognition of abdominal injuries is based on common clinical symptoms).

Abdominal Injuries