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Biomedical subjects

I Isakow

Publications and source records attributed to I Isakow.

9 recordsLinked to original sources

Posttraumatic recurrent corneal erosion, #2. Ultrastructural findings in epithelium and stroma.

Basement membrane deficiency, accompanied by alterations in basal epithelial cells, was shown in a case of posttraumatic recurrent corneal erosion (RCE) by Goldman et al. [1] and in other corneal disorders [2, 3, 4, 5, 6]. We have previously [7] described a case of posttraumatic RCE which was treated successfully by surgical procedure. This report presents electron microscopic observations of the excised tissues which indicate significant changes in the corneal stroma as well as in its epithelium and basement membrane.

Cornea↗

Simultaneous trabeculectomy and cataract extraction.

A combined trabeculectomy and cataract extraction was performed on 46 eyes of 39 patients. The average follow-up period was of 27 months. The intraocular pressure remained controlled without the need of postoperative medication in 33 eyes (71.74%); 12 eyes (26.09%) needed further medical treatment; and in one eye the pressure remained uncontrolled and further surgery was necessary. After surgery the visual acuity improved considerably and the complications were few. The combined procedure has many advantages. The patient is cured by one surgical procedure, his visual acuity improves, his intraocular pressure is reduced to normal, and he is relieved from the need for medication postoperatively. By a single stay in hospital and by reducing the number of postoperative medical routine controls the expenses are reduced considerably. Owing to these advantages the combined procedure deserves to be considered in cases of glaucoma and cataract.

Aged↗

Posttraumatic recurrent corneal erosion. 1. Clinical and histological studies.

A severe, bilateral, posttraumatic recurrent corneal erosion in a 29-year-old woman was treated by bilateral lamellar keratectomy. The surgical procedure was performed first in the right eye. Under local anesthesia the defective corneal region stained by fluorescein was completely removed. It comprised a lamella measuring 2 X 3 mm and included epithelium and underlying superficial stroma, both of which showed abnormal features. Following this procedure, her right eye was asymptomatic for over 6 yr. Surgical procedure in the left eye was performed in the same manner except that only a part of the stained cornea containing superficial layers of epithelium was removed, in order to prevent central scarring. Despite surgery, the recurrent painful attacks in this eye continued.

Adult↗

Photocoagulation in retinal vein occlusion.

Photocoagulation was used to treat 40 eyes, 20 with central and 20 with branch vein occlusion. Panretinal photocoagulation was used over the fundus in central vein occlusion, and regional photocoagulation over the affected area in branch vein occlusion. No complications were observed during a follow-up period of 8 to 24 months. Recent as well as long-standing cases with macular edema were treated. Visual acuity improved in 85% of eyes with central vein occlusion and 80% of eyes with branch vein occlusion. Visual acuity results were more satisfactory with early treatment.

Aged↗

Prophylactic antibiotics in cataract surgery.

The value of preoperative cultures, sensitivity tests and prophylactic preoperative antibiotic treatment was evaluated in a group of senile, uncomplicated lens extractions. Sulfacetamide or a mixture of chloramphenicol and polymixin were applied preoperatively for 1 week and an injection of penicillin and streptomycin was given postoperatively. A control group of 140 cases without treatment was also studied. No postoperative infections developed in either group. The number of pathogenic cultures was significantly smaller in the treated group as compared with the untreated one; the mixture of chloramphenicol and polymixin B sulfate was found to be superior to sulfacetamide, different clinical data was compared in the two groups. No postoperative infections developed in either group.

Aged↗