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Biomedical subjects

I Iu Kolesnikova

Publications and source records attributed to I Iu Kolesnikova.

9 recordsLinked to original sources
PubMed2006

[Quantitative-qualitative assessment of duodenogastric reflux at 24-h pH-metry].

AIM: To study characteristics (other than duration) of duodenogastric reflux (DGR), correlations of secretory function and DGR characteristics with gastroduodenal disorders (ulcer, chronic hyperacid gastritis). MATERIAL AND METHODS: A total of 110 patients were examined with 24-h pH-metry: 68 patients with duodenal ulcer (DU), 15 patients with gastric ulcer (GU), 27 patients with chronic hyperacid gastritis (CHG). Mean levels of pH and duration of hyperacidity in the body and an antral part of the stomach, duration of DGR, pH in the body and antral part of the stomach depending on DGR severity were studied. RESULTS: DGR was registered almost in all the patients with DU, GU and CHG. Groups of the patients differed by duration and height" of the DGR. CONCLUSION: Patients with DU are characterized by low refluxes which do not reach gastric body.

Adolescent↗
PubMed2005

[On correlations between the clinical course of peptic ulcer and the patients, compliance and quality of life].

The article is dedicated to changes in life quality (LQ) and mental status, and to forming of various types of response to the disease in patients with benign and unfavorable course of peptic ulcer (PU). The subjects were 140 patients in acute phase of PU, in 66 of whom the course of the disease was benign, and in 74--unfavorable. In both groups there were patients with low and satisfactory LQ. High level of nervousness was typical of patients with low LQ and benign course of the disease. Patients with satisfactory LQ and unfavorable course of the disease were characterized by minor personality changes, but developed an agnostic response to the disease much more frequently. Reduction of compliance was found mainly in patients with low LQ and an agnostic response; this should be taken into consideration while correcting the therapy.

Adolescent↗
PubMed2003

[Role of duodenogastric reflus in pathogenesis of duodenal ulcer].

Duodenal ulcer is characterized by certain recurrence and occurs more often in men than in women. One can assume that functional changes, which are characterized by the seasonal nature and sex differences, play some role in its pathogenesis. There was a study of the duodenogastric reflux role in the pathogenesis of duodenal ulcer. It was revealed that duodenal reflux is provoked in about one half of patients sent for an endoscopic examination, less frequently--in spring and autumn, and least of all--in male patients with duodenal ulcer during seasons of the maximum frequency of duodenal ulcer exacerbations. The frequency of duodenogastric reflux provocation went down on days of geomagnetic storms. One could observe certain dependence between the extent and duration of reflux, on the one hand, and clinical registration of the disease, on the other hand.

Duodenal Ulcer↗
PubMed2003

[Gastroduodenal reflex in duodenal ulcer and chronic hyperacidic gastritis].

AIM: To study motor and secretory function of the stomach and duodenum in duodenal ulcer (DU) and chronic hyperacidic gastritis (CHG). MATERIAL AND METHODS: Autonomic nervous system was studied and esophagogastroduodenoscopy, 24-h intragastric pH-metry were made in 42 DU and 20 CHG patients. RESULTS: In comparable secretion, the patients of the above groups differed by severity and frequency of duodenogastric reflux (DGR). Grave and moderate DGR was typical for CHG and DU in the absence of complications. Minimal DGR occurred in DU with complications. CONCLUSION: DGR severity may be of prognostic significance for DU course.

Chronic Disease↗
PubMed2002

[Circadian monitoring of intragastric pH in evaluation of efficiency of antisecretory therapy of duodenal ulcer].

Inhibitors of proton pump are thought "golden standard" in the treatment of ulcer. Usage of omeprasol generics in standard doses sometimes fail to adequately reduce acid production. In pain persistence in patients with duodenal ulcer receiving standard antisecretory therapy it is effective to control it with 24-h intragastric pH-metry which either indicate the necessity of dose correction or another cause of pain (concomitant affections as a rule). As shown by 24-h pH-metry, a new generic of omeprasol, omeprus, is close by effectiveness to the known drug omeaz.

Adult↗
PubMed2001

[Life quality, mental status and specific features of the course of diseases in patients with peptic ulcer].

At present, medicine pays a great attention to studies into life quality (LQ) in patients. A relationship is examined between LQ and the course of a disease and the personality traits of a patient. Sixty patients with peptic ulcer (PU) were included in this study. The questionnaires filled by the patients were used to assess their LQ and the factors that modify LQ to the greatest degree, as well as personality traits and pain perception in patients. The same aspect of the patients' life was additionally evaluated by physicians. Studies indicated that LQ in patients was regularly decreased with their worse health. At the same time, there were increases in the degree of emotional stress and in the proportion of patients with depressive-hypochondriac personality traits and higher pain perception. At the same time the patients' emotional experiences and neurotization rather than the course of a disease were found to predominantly affect LQ. This is likely to be borne in mind in managing such patients.

Adult↗
PubMed2001

[Somatoform disorders in ulcers].

We studied correlations between psychoemotional and vegetative disorders in ulcer. 60 patients with ulcer varying in severity were examined. The severity was judged by the disease history, endoscopic and x-ray findings. Emotional and personality characteristics were evaluated by answers in special questionnaires, vegetative deviations were studied with special tests, scale, cardiointervalogram. It was found that more severe course of ulcer correlated with growing vegetative dysfunction. The progressive ulcer course ran with predominance of sympathetic autonomic nervous system and is accompanied with marked psychoemotional tension and development of anxiodepressive personality traits.

Adult↗
PubMed1995

[Neurophysiological mechanisms of the cortical-subcortical interrelationships in the organization of behavior].

Specific intersystem relationships seem to exist characterising interrelationships among neurons within pools of which plasticity of a single neuron is able to maintain integration processes of the whole system. The neurons under study seem to become united into various functional blocks during different phases of conditioned behaviour which determines a formation of a dominant condition of the centres and vectors of a specific behavioural action in a given situation and at a given time.

Animals↗