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I Käufer-Weiss

Publications and source records attributed to I Käufer-Weiss.

5 recordsLinked to original sources
PubMed1998

[Significance and possibilities of histopathologic diagnosis in breed-specific skin diseases].

An increasing number of punch biopsies is submitted for histopathology. Results are often disappointing for the veterinary pathologist as well as the referring veterinarian. Inappropriate timing of sampling, selection and preparation of the biopsy site, type of biopsy, biopsy technique and fixation as well as incomplete histories often contribute to insufficient diagnosis and interpretation of skin lesions. The introduction of this review gives an overview of the requirements for a satisfying evaluation of skin lesions and the limits of diagnostic histopathology on skin samples, especially punch biopsies. The second part summarizes more frequent dermatohistopathological diagnoses according to the pattern analysis of skin lesions, using examples of skin diseases with breed predisposition. Among the described skin lesions are the dermatoses associated with endocrine dysfunction, cutaneous mucinosis, Vogt-Koyanagi-Harada-like syndrome, alopecia of color mutants, dermatomyositis, granulomatous sebadentitis, Malassezia dermatitis, pyoderma and atopic dermatitis.

Animals↗
PubMed1992

[Light and electron microscopic studies of calf kidneys after exposure to subtoxic lead levels].

Eight calves were fed from the fourth to the twentieth week of age a milk powder diet containing 40 mg lead acetate per kg dry substance. This is twice the lead concentration legally permitted. In average, each animal has daily taken up 0.834 mg lead per kg body weight. Eight calves were used as controls. The animals gained the usual fattening weights and did not show clinical symptoms. Beginning with week 14, increased levels of blood urea were encountered in the animals which received lead in their diet. Morphologically, severe renal lesions were found in these calves. The kidneys were increased in weight, pale and of firm consistency. Histologically, fibrosis and periglomerular interstitial non-purulent nephritis were found. Light- and electronmicroscopically, numerous intranuclear inclusion-bodies typical for lead poisoning were demonstrated in epithelial cells of proximal tubules. The results show, that daily uptake of less than 1 mg lead per kg body weight must be considered as a toxic dose for calves, and not 5-7 mg as stated in literature.

Animal Feed↗
PubMed1991

On the pathogenesis of anaemia and leukopenia in filarial (Litomosoides carinii) infection of Mastomys natalensis.

Mastomys natalensis infected with the filarial parasite Litomosoides carinii show anaemia and leukopenia. Alterations start with the onset of microfilaraemia. Anaemia is temporally macrocytic (up to 80 days after infection), subsequently normocytic and hypochromic, accompanied by reticulocytosis. Increased intravascular haemolysis (i) and functional disorders of the haemopoetic system (ii) are involved in the pathogenesis. i: Circulating erythrocytes showed increased osmofragility. Hypoglycaemia demonstrated in parasitaemic animals may be one reason. ii: Histological and electron microscopical investigations of the bone marrow revealed markedly enhanced haemopoiesis in infected animals. However, a high proportion of cells was found pathologically altered already beginning in the late prepatency and increasing in the further course of infection. Thus, dyshaemopoiesis may result in the production of morphologically and functionally aberrant cells which are rapidly eliminated by the MPS which is highly activated in L. carinii infected M. natalensis.

Anemia↗
PubMed1989

[Accidental thymus involution in calves].

In 149 necropsied calves (age 0 to 28 days) a reduced thymus was found. The absolute thymus weights varied between 6 and 220 g. The relative thymus weights (applied to bodyweight) were between 0.02 and 0.52% (healthy controls 0.24 to 0.67%). The histological changes resemble those of accidental thymus involution. Corresponding to the duration of the disease and/or loss of body weight of the animals there is an increase of lymphocyte depletion. The accidental thymus involution is presumed to be a morphological expression of a secondary immunodeficiency.

Animals↗