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Biomedical subjects

I Kacprzak-Bergman

Publications and source records attributed to I Kacprzak-Bergman.

At least 19 recordsLinked to original sources
PubMed1997

Polymorphism of the fourth component of complement (C4) and three clinical pictures of hepatitis B virus infection in children.

The fourth component of complement (C4) phenotype and allele frequencies were studied in 3 groups of unrelated children affected with hepatitis B virus (HBV) infection (25 with glomerulonephritis (GN), 39 with chronic active hepatitis (CAH), 24 with Gianotti-Crosti syndrome (GS-S)) and in 100 unrelated healthy individuals (H). Ten phenotypes in GN, 14 in CAH, 10 in GC-S and 23 in H were found. Some rare phenotypes appeared in the individual cases of ill children. Statistical analysis was performed by chi-square test. Each group was compared to the others. We found significantly higher frequency of the A3B2,Q0 phenotype in CAH than in H as well as significant increase of the A x 4 gene frequency in GC-S as compared to H. However, these events could be caused by limited number of tested patients. We suspect that the association between C4 alleles and immune-complex diseases, studied here, does not rather exist.

Alleles↗
PubMed1996

Frequency of complement third component (C3) and properdin factor (BF) phenotypes in patients with various clinical manifestations of HBV infection.

Four groups of children were tested for the distribution of C3 and BF phenotypes: HBV-infected patients with Gianotti-Crosti syndrome, with CAH and with glomerulonephritis, and healthy children. The frequency of the phenotype C3F was significantly higher in children with Gianotti-Crosti syndrome in comparison with healthy children. The frequency of the phenotype BFS was significantly higher in patients with glomerulonephritis than in individuals with CAH. The difference between the frequency of the BFS phenotype in glomerulonephritis patients and that in healthy subjects neared significance. We suggest that the carriers of these phenotypes are characterized by susceptibility to some immune complex diseases associated with HBV infection.

Acrodermatitis↗
PubMed1995

Frequency of Gm and Km phenotypes in children with mumps meningitis.

Children with mumps meningitis, with mumps without meningitis and healthy subjects were examined for Gm 1, 2, 3, 5, 21 allotypes and for the Km 1 allotype. The comparison of the frequencies of Gm and Km phenotypes in three tested groups (each to the other) did not reveal significant differences. An association between mumps meningitis and the Gm or Km phenotypes was not found.

Adolescent↗
PubMed1995

[Slow development of multiorgan tuberculosis in an infant].

Slowly developing tuberculosis in a BCG-vaccinated infant was analysed in a 2-month-old child suffering from cervico-lymphadenitis. It was diagnosed after 8-months period of non-specific treatment as tuberculosis. Further observation revealed severe forms of disease-miliary tuberculosis and meningoencephalitis. Familial contact with tuberculosis was established. The outcome after 9 months of anti-tuberculosis therapy was successful.

Humans↗
PubMed1992

HLA-DR antigens in children with mumps meningitis.

The frequency of HLA-DR antigens was studied in 54 patients with mumps meningitis, and in two control groups. The first control group comprised 333 randomly chosen subjects while the second group was composed of 46 subjects who have passed mumps without meningitis. The DR5 antigen was more frequent in patients than in the second control group with relative risk of 2.4 and significance at the level of p < 0.05. The p value became insignificant after the correction for the number of antigens investigated.

Child↗
PubMed1989

[Systemic candidiasis with meningeal involvement in a newborn infant].

The newborn with sepsis (E. coli) and salmonellosis was described. After treatment with broad-spectrum antibiotics it was suffered from Candida albicans (Meningitis with Hydrocephalus internus, Chorioretinitis and Ostitis). The authors difficulties connected with diagnosis and anti-fungal therapy have showed. They have punctated the necessity of combined anti-mycotic therapy.

Candidiasis↗
PubMed1982

Some factors of immunopathogenesis of infectious mononucleosis in children.

Sixty-eight children with the symptoms of infectious mononucleosis were examined. In 25 of them anti-EBV antibodies were found and in 10 heterophilic antibodies. In serum of 16 children sero-positive to EBV A, M, G, D immunoglobulins were determined as well as T and B lymphocytes. A statistically significant increase in the number of B-IgA, B-IgG and B-IgM lymphocytes, augmentation of T lymphocyte number and polyclonal hypergammaglobulinemia were detected.

Adolescent↗