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Biomedical subjects

I Kaffe

Publications and source records attributed to I Kaffe.

At least 19 recordsLinked to original sources

Interpretation of bitewing radiographs. Part 1. Evaluation of the presence of approximal lesions.

OBJECTIVE: Bitewing radiographs are the main tool for approximal caries detection. However, interpretation of findings is affected by numerous factors, such as beam angulation, exposure conditions, morphologic variations, etc. The objective of the present study was to compare the ability to detect virtually identical, artificial lesions in different tooth surfaces. METHODS: The in vitro model included preparation and radiologic evaluation of approximal artificial lesions in premolars and molars in depths ranging from 0.00 mm to 1.50 mm. RESULTS: Significant differences were found in the prospect of a lesion detection between the different lesion depths (p < 0.0000) and between the different surfaces examined (p < 0.05). The interaction between lesion depth and tooth surface was significant at the 0.0001 level (ANOVA with repeated measures). CONCLUSIONS: The results indicate that initial approximal lesions of uniform size are more readily detected in premolars than in molars and that the chance of an incipient lesion to remain undetected is twice as high in molars than in premolars.

Analysis of Variance

Interpretation of bitewing radiographs. Part 2. Evaluation of the size of approximal lesions and need for treatment.

OBJECTIVE: The decision to treat initial approximal carious lesions is based mainly on interpretation of bitewing radiographs. In a previous report, it was shown that artificial approximal lesions of uniform size are more readily detected on radiographs in premolars than in molars. The objective of the present study was to compare the ability to evaluate the depth of similar size artificial lesions on radiographs and reach decisions concerning treatment, in premolars and molars. METHOD: Clinicians were asked to evaluate on radiographs, the size of in vitro prepared artificial lesions, and decide at which point they would perform a restoration. RESULTS: Significant differences were found in the evaluation of lesion depth between different tooth surfaces. The interaction between lesion depth and tooth surface originated from the examiners' trend to score same size lesions as penetrating deeper into the tooth in premolars than in molars. The probability of the examiners to decide on restorative treatment in shallow lesions (0.25 mm, 0.50 mm) was higher in premolars than in molars. CONCLUSIONS: The findings suggest that clinicians evaluate initial lesions as being deeper and more prone to treatment in premolars than in molars.

Analysis of Variance

Radiologic features of central giant cell granuloma of the jaws.

The radiologic features of central giant cell granuloma (CGCG) have not been clearly defined, and conflicting descriptions appear in the literature. This study analyzes the radiologic and clinical features of 80 cases of CGCG. In nearly 50% of the cases the lesion is located in the posterior area of the jaws, that is, the molar, ramus, and tuberosity, and not in the deciduous teeth-bearing area as was accepted in the past. Only 51% of CGCGs are multilocular, and the frequency of these lesions is significantly higher in the mandible than in the maxilla. The correlation between the lesion's size and its locularity is statistically significant, and larger lesions assume a multilocular appearance. Only 6% of the lesions crossed the midline of the jaws, a feature that was considered in the past as typical for CGCG.

Adolescent

Influence of soft tissue on density and relative contrast between gutta-percha and dentin images. An in vitro study.

The current ANSI/ADA standard for density of gutta-percha (GP) has been found to be insufficient for clinical purposes. Furthermore, it does not take into account the possible influence of soft tissue on the image of GP in the root canal. The present study evaluated the density of GP according to the standard and the influence of soft tissue on the contrast between GP and dentin in vitro. The optical density of all tested GP brands was higher than the recommended standard. Soft tissue significantly influenced the relative contrast between dentin and GP and a decrease of more than 10% was observed when soft-tissue-equivalent phantom was added (p<0.000). A test simulating a clinical condition is recommended for improving the standard for the density of GP.

Absorptiometry, Photon

Radiographic features of anterior buccal mandibular depression in modern human cadavers.

The anterior buccal mandibular depression (ABMD) becomes significant when evaluating edentulous patients prior to implant insertion. The features of the ABMD in dry mandibles from ancient populations have been reported. In the present study the prevalence and radiological appearance of the ABMD and the influence of soft tissue superposition on its radiological detectability in the jaws of modern human cadavers were evaluated. The prevalence of ABMD was 32%. The presence of soft tissue significantly influenced the radiopacity of the ABMD area and the degree of definition of the borders (p=0.0003 and 0.0001 respectively). Changes in the trabecular pattern were observed in 36% of the cases without soft tissue compared with 29% with soft tissue. The ABMD was more readily detected on CT scans than on conventional periapical or panoramic radiographs.

Age Distribution

Anterior buccal mandibular depression (ABMD). Anatomic and histologic features.

The anterior buccal mandibular depression (ABMD) is a bilateral symmetrical depression located anterior to the mental foramen and extends under the alveoli of the first premolar to the central incisor. The prevalence, dimensions and contents of the ABMD in cadavers of fetuses and adult modern humans were evaluated. ABMD was found in all fetuses and in 31.8% of adults. The average dimensions of the ABMD in adults were depth 2.36 mm, width 5.44 mm and length 12.43 mm. The present study contributes to a better evaluation of the differential diagnosis and treatment planning in the anterior region of the mandible. A possible etiology for the development of ABMD is suggested.

Aged

Radiologic features of central odontogenic fibroma.

The central odontogenic fibroma is a rare benign neoplasm that is considered to be derived from mesenchymal dental tissue. This study reviews and analyzes the radiologic features of 51 cases (5 new cases and 46 from the literature). Central odontogenic fibroma appears in both the mandible and maxilla (55% and 45%, respectively). In the maxilla it has a tendency to involve the anterior area, whereas in the mandible the molar and premolar areas are the most prevalent sites. The majority of central odontogenic fibromas are unilocular radiolucent lesions with well-defined borders, but they may also appear as multilocular lesions and in rare instances may exhibit a mixed radiolucent/radiopaque appearance with poorly defined or diffused borders. The great variability in radiologic appearance of the central odontogenic fibroma means that it should be considered in the differential diagnosis of all radiolucencies found in the jaws.

Adolescent

Location of the mandibular foramen in panoramic radiographs.

The reliability of two panoramic x-ray machines (Philips Orthoralix SD Ceph and Gendex Panelipse II) for determination of the location of the mandibular foramen was studied with the use of human dry mandibles. A significant correlation was found between the location of the mandibular foramen in the radiograph and the narrowest anteroposterior dimension of the ramus. A linear logistic regression equation was developed that could predict the actual location of the mandibular foramen from the radiographs. This finding will improve treatment planning of surgical splitting or fracturing of the ramus in cases that require orthognathic surgery provided the surgeon is aware of which panoramic machine was used. The Philips Orthoralix SD was found to be more reliable for this purpose than the Panelipse II (R2 = 0.94 and R2 = 0.87, respectively, in the vertical dimension and R2 = 0.87 and R2 = 0.75, respectively, in the horizontal dimension.

Humans

Radiological findings in jaws and skull of neurofibromatosis type 1 patients.

Maxillary and mandibular lesions in neurofibromatosis Type 1 (NF1) in patients are described. Radiographic manifestations include radiolucent lesions with well-defined, poorly-defined or irregular diffuse borders. Mandibular lesions were not associated with the inferior alveolar nerve as it coursed within the mandible. In three patients the lesions extended considerably into the cranial bones. The necessity for routine radiographic and CT evaluation of NF1 patients is emphasized.

Adolescent

Radiologic features of desmoplastic variant of ameloblastoma.

Desmoplastic variant of ameloblastoma is a newly described variant characterized by unique histologic and radiographic features. This study reviews and analyzes the clinical and radiographic features of 15 cases of desmoplastic variant of ameloblastoma (14 cases from the literature and one case from our files). Desmoplastic variant of ameloblastoma shows a predilection for the maxilla and has a tendency to occur in the anterior region of the mandible and maxilla. Radiographically, almost all desmoplastic variant of ameloblastomas exhibit a mixed radiolucent-radiopaque appearance. Most show poorly defined or diffused borders and are mistakenly diagnosed as fibro-osseous lesions.

Adult

Extraction site healing in rats. A radiologic densitometric study.

The present study uses a simple, objective method to radiographically evaluate the changes that occur during socket healing in rats. Mandibular left first molars were extracted in 35 Wistar rats, which were then sacrificed at 0, 7, 14, 21, 28, 45, and 60 days after surgery. Mandibles were removed, placed on an ANSI size 2 film, and exposed with an aluminum step-wedge, 0.5 to 3.0 mm. Socket density was measured with a digital densitometer and related to the equivalent density of aluminum. Increased density of the image of the apical and crestal areas of the socket was observed on day 7. Maximum density was reached by day 28 in the apical area; in the crestal area, density increased at a slower rate. The density changes found in the present study agree with the known histologic reports of socket healing in rats. Densitometric evaluation of extraction socket healing, using a step-wedge with 0.5 mm increments, is a useful and reliable tool to objectively assess bone formation and mineralization.

Aluminum

Recovery of the infraorbital nerve after zygomatic complex fractures: a preliminary study of different treatment methods.

The infraorbital nerve (ION) is often involved in trauma to the zygomatic complex (ZC), resulting in sensory disturbance of the area innervated by it. The purpose of the study was to compare the incidence of persistent sensory disturbance after recovery from isolated simple fractures of the ZC, with four treatment methods: 1) closed reduction via subcutaneous approach without fixation; 2) open reduction via subcutaneous approach without fixation; 3) open reduction via oroantral approach and support of the complex by an intraantral Foley catheter; and 4) open reduction via Gillies approach with fixation of the frontozygomatic (FZ) fracture with wire osteosynthesis, and open reduction via Gillies approach with fixation of the FZ fracture with miniplate osteosynthesis. Analysis revealed that patients treated with miniplate osteosynthesis exhibited a trend for higher recovery rate of the (ION) than with the other three methods. No significant differences were found among the other three methods.

Bone Plates

Comparative evaluation of different radiographic projections of zygomatic complex fractures.

Diagnosis of zygomaticomaxillary fractures is a major problem in radiographic interpretation. The purpose of the present study was to evaluate several radiographic examinations performed in an emergency room to diagnose zygomatic complex (ZC) fractures, in order to determine which is the single best radiographic projection for this purpose. Radiographs of 160 patients with ZC fractures were evaluated retrospectively. The modified P-A projection (10 degrees-20 degrees) provided a clear image of the frontozygomatic, infra-orbital rim and temporozygomatic fracture lines in all cases. In half the cases, the modified P-A projection also clearly demonstrated the fracture line in the zygomatic maxillary buttress. On the other hand, the Water's view demonstrated the fracture line in the zygomatic maxillary buttress and the temporozygomatic bone in all cases, but in only 65% of the cases was the fracture line in the infra-orbital rim and the frontozygomatic bones shown. The modified P-A projection was found to be the single best radiographic examination that should be performed in the emergency room to diagnose ZC fractures.

Evaluation Studies as Topic

Long-term effect of desalivation on extraction wound healing: a densitometric study in rats.

The study evaluates radiographically the long-term changes that occur during the healing of tooth sockets in a desalivated rat model. Experimental rats underwent sialadenectomy of the submandibular and sublingual glands and ligation of the parotid ducts. Mandibular left first molars were extracted and the rats killed at 0, 14, 21, 28, 45 and 60 days post-extraction. The mandibles were removed, cleaned of soft tissue, placed on a size 2 dental X-ray film and exposed together with an aluminium stepwedge 0.5-3.0 mm. Socket density was measured using a digital densitometer and related to the equivalent density of aluminium. The density of the image of the apical area of the socket was similar in control and desalivated groups (P > 0.05) throughout the study. However, the density of the image of the crestal area of the socket was lower (P < 0.01-0.001) between days 21 and 60 in desalivated rats. This suggests that desalivation causes a long-term delay in socket healing.

Absorptiometry, Photon

The significance of idiopathic osteosclerosis found in panoramic radiographs of sporadic colorectal neoplasia patients and their relatives.

Osteosclerotic lesions in the mandible are reported with increased frequency in patients with colorectal neoplasia. Panoramic radiography has been suggested to detect high-risk patients among relatives of patients with hereditary adenomatous disease and sporadic colorectal cancer. The present study was undertaken to compare the incidence of idiopathic osteosclerotic lesions in patients with sporadic colorectal cancer and their first-degree relatives with the incidence in the general population and to determine whether panoramic radiographs are a reliable method to screen for early detection of risk of colorectal cancer. A total of 283 patients were interviewed and radiographically examined. Idiopathic osteosclerosis appeared in significantly increased incidence only in patients with colorectal cancer or adenomas and a first-degree relative with CRC (chi 2 = 7.214; p less than 0.01, and chi 2 = 4.1827; p less than 0.05 respectively). The incidence was not increased in first-degree relatives of patients with colorectal cancer or adenoma. Therefore panoramic radiographs cannot be the only screening tool for early detection of patients at high risk of colorectal cancer.

Adenoma

The anterior buccal mandibular depression: physical and radiologic features.

The anterior buccal mandibular depression (ABMD), an anatomic variation not previously mentioned in the dental literature, is considered. Its physical and radiologic configuration is evaluated, and its significance in the differential diagnosis of radiolucent lesions in the anterior portion of the mandible is discussed. The general prevalence of ABMD was found to be 19.8%, with a significantly higher prevalence in children (p less than 0.001). In the majority of cases, the depression was radiologically detected. The radiopacity of the area was significantly dependent on depth of the depression (p less than 0.001). The radiographic image of the ABMD resembles, in many cases, the image of the less common anterior lingual salivary gland depression. The relatively high frequency of the ABMD indicates the importance of recognizing its radiologic features.

Adolescent

Prediction of efficacy of bitewing radiographs for caries detection.

Although bitewing (BW) radiographs play an indispensable role in the detection of interproximal caries, it is not always clear when they should be made. The present study was designed to test the hypothesis that a person's caries and restorative history may be predictive of his or her caries future. Full-mouth radiographic examinations (FMX) and subsequent BW radiographs from 349 adults (age 20 or more) selected at random were examined. Possible risk factors for caries recorded for each patient included the number and type of carious lesions and the restorative experience of the patient. Linear logistic regression models were evaluated to estimate the efficacy of the possible risk factors as predictors of the presence of caries on the BW radiographs. Of the 349 adults examined, 91 (26%) had one or more new carious lesions at the time of their BW examination. The probability of caries in this population at the time of the BW examination increases both with lengthening interval between the FMX and the BW radiographs and with the number of restorations at the time of FMX. A regression model was adopted that estimates the probability of caries being detected on BW radiographs. We found that to provide the most good for the most patients (minimize cost), the threshold level for ordering follow-up radiographs should be when the probability of detecting caries is 5%. It may be seen that even when a person has no caries or restorations at the time of the FMX there will be a 5% chance that BW radiographs will reveal the presence of caries 1.5 years later. The 5% threshold is reached sooner in the presence of caries or restorations.

Adult

Densitometric measurement of radiopacity of Gutta-percha cones and root dentin.

National and international standards require that gutta-percha cones be sufficiently radiopaque to be distinguished from natural structures such as dentin and to permit evaluation of the density of the root canal filling. Discs, 1-mm thick, made from 15 commercial and experimental brands of gutta-percha cones, were tested for their compliance with the requirements. The radiopacity of 1-mm thick root dentin slabs was similarly measured with a photo-densitometer. All radiographs were made on D-speed occlusal film and replicated on E-speed film. The mean radiopacity of the gutta-percha discs on D-speed film was 7.26 mm of aluminum equivalent and 7.53 mm on E-speed film, greatly exceeding the minimal requirement of 3 mm. The difference in the values obtained with the two film types was not significant, suggesting that E-speed films may be used for the test. Dentin slabs were uniform in their radiopacity, equivalent to 1 mm of aluminum, confirming previous findings. In view of complaints of insufficient clinical performance, the present minimal requirement for radiopacity of gutta-percha cones seems too low.

Densitometry