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Biomedical subjects

I Karastanev

Publications and source records attributed to I Karastanev.

At least 19 recordsLinked to original sources
PubMed1986

[Prevention of atrial flutter with Chinidin retard].

The action of the preparation Chinidin retard, tablets of 0.250, was studied with a view to its effects of preserving the recovered sinus rhythm after regularization in 32 patients with atrial flutter, as well as its effect on central hemodynamics and functions of parenchymal organs. The successful anti-recurrence treatment and the maintenance of lasting sinus rhythm after regularization in 90.6 per cent of the patients for more than 6 months with only 2 tablets daily, provided grounds to recommend chinidin retard as an agent of choice for long-term prophylaxis against the paroxysm of atrial flutter. The preparation has a lightly manifested negative inotropic action, but with the doses administered--it leads to no left-ventricular dysfunction. The long-term treatment with chinidin retard has no toxic effect on parenchymal organs.

Atrial Flutter↗
PubMed1979

[Nephropathy in a patient with IgD-myeloma].

A myeloma nephropathy in the rarely found paraproteinemia, class IgD is described for the first time in our country, manifested clinically from the very onset of the disease and advancing with a series of peculiarities, causing differential-diagnostic difficulties. The cytostatic treatment applied was with a good effect.

Humans↗
PubMed1979

[Malignant, rapidly progressing nephritis in Schönlein-Henoch disease].

A case of malignant quickly progressing Henoch-nephritis is described, with a lethal end one and a half month after the initial manifestations. The disease develops with a clinical picture typical for systemic vasculitis, with joint-pain, skin-rash and grave abdominal syndrome, being the reason for unnecessary surgical intervention. The renal changes originate even at the very beginning of the disease and are clinically characterized, besides the exceptionally quick evolution, by the picture of acute renal insufficiency with progressing azotemia, severe electrolyte disturbances and anemic syndrome and pathomorphologically by the picture of severe diffuse intra- and extracapillary proliferative glomerulitis. The treatment with antihistamine preparations, heparin and corticosteroids failed to give an effect.

Adult↗