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Biomedical subjects

I Kempelen

Publications and source records attributed to I Kempelen.

6 recordsLinked to original sources

[Effect of fibroscopic sclerotherapy of hemorrhaging esophageal varices on survival in alcoholic liver cirrhosis (comparative retrospective study)].

UNLABELLED: Between 1983 and 1992 altogether 638 alcoholic cirrhotic patients had been treated because of acute esophageal variceal bleeding. In 96 cases the treatment were carried out in the following circumstances; volume and coagulation factor substituate, vasopressin or glypressin and nitroglycerin, urgent endoscopy and ballontamponade but in 47 cases an urgent sclerotherapy were also performed. The survival, cases of rebleeding,-from the first bleeding events-of the 49 nonsclerosed patients were compared to those of the 47 sclerosed one. CONCLUSIONS: 1. The endoscopic sclerotherapy proved to be life-saving procedure. 2. Within 30 days the nonsclerosed patients died twice as much number than the slcerosed patients. 3. The lengths of the survival period were found four and half times so long at the sclerosed patients than in nonsclerosed patients (535 versus 125 days). 4. The numbers of the rebleeding were not less at the sclerosed patients than the nonsclerosed subjects. 5. The lengths of the nonbleeding period was found triple so long at the sclerosed patients than in nonsclerosed patients. 6. The survival of the "Child C" patients at the sclerosed and nonsclerosed patients, too. The authors come to conclusion that by the fiberendoscopic sclerotherapy an increase in the survival time of the patients with acute esophageal variceal bleeding in alcoholic cirrhosis can be achieved.

Acute Disease↗

[Treatment of chronic alcoholic pancreatitis with a new acid-resistant pancreatin product].

The authors summarised pathophysiology and therapy possibility of the chronic alcoholic pancreatitis. They introduce a new product of pancreatin use for treatment of chronic alcoholic pancreatitis. The aim of this prospective study was to asses the efficacy of this new drug in the treatment of chronic alcoholic pancreatitis. The treatment was carried out by new pancreatin product containing 10,000 FIP U lipase, 9000 FIP U amylase, and 500 FIP E protease. During the study 30 patients--suffering from alcoholic pancreatitis--were treated. They received, two tablets three times daily in a period of two weeks. The following parameters were observed and compared before and after the period of treatment: complaints of the patients, the characteristics of the stool (daily weight, frequency, fat contents, consistency) the change of the body weight and degree of abdominal pain. These parameters were compared using a score-system, before and after the period of treatment. The authors could analyse the data of 21 patients. It was proved that there was a significant decrease in frequency, daily weight and fat contents of the stool and in abdominal pain. There was not significant change in the body weight. The authors concluded that this new product is a good pancreatin preparation which is useful and suitable for effective treatment of chronic alcoholic pancreatitis, if the patient keeps abstinence.

Alcoholism↗

Early diagnosis of cancer by gastricbiopsy.

On the basis of 350 gastric biopsies the difficulties of early diagnosis of cancer are discussed. The technical and morphological stumbling blocks of evaluation are reviewed. The differences between the gross and microscopic diagnoses, the more important causes of histologic error are dealt with.

Adenocarcinoma↗