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Biomedical subjects

I Kiso

Publications and source records attributed to I Kiso.

At least 37 records · Page 2Linked to original sources
PubMed1978

Blood flow and pressure measurements of right coronary artery to left ventricle fistula.

A case of a dilated and tortuous right coronary artery to left ventricle fistula was surgically repaired. Preoperative intracoronary pressure measurements showed a sudden depression of diastolic pressure in the terminal part of the right coronary artery. Intraoperative mean right coronary flow was recorded as 315 ml/min. After repair of the fistula, blood flow measurements showed only 35 ml/min, which suggested that a large amount of blood was stolen by the fistula. Although systolic and diastolic murmurs only were heard in our patient, continuous murmurs have been noticed by some observers. From a study of the preoperative physical findings, intraoperative coronary flow measurements, and other operative findings, the genesis of heart murmurs relating to this type of anomaly is discussed.

Arteriovenous Malformations↗
PubMed1976

An extravascular left ventricular assist device.

The hemodynamic efficacy and prosthesis-vessel interaction of a pneumatically activated circulatory assist device was investigated in 12 acute and 12 chronic studies in dogs. A polyurethane balloon encased in Dacron-velour cloth was fastened to the descending thoracic aorta with a spiral wrapping of Dacron graft material. Diastolic augmentation was provided by rhythmic inflation and deflation of the balloon. Hemodynamic results, based on 5 dogs with experimental myocardial ischemia, showed that left ventricular systolic peak pressure decreased by 8.2 +/- 1.9%, cardiac output increased by 13.1 +/- 2.8%, and circumflex coronary artery flow rose by 17.5 +/- 2.5%. In the chronic experiments the prosthesis was asynchronously but continuously activated from one to sixteen weeks at 74 cycles per minute. Postmortem examination of the implantation site in all 12 dogs showed that necrosis had developed but was limited to the outer half of the medial layer beneath the pumping chamber and that the aortic wall was compressed to about 70% of its original thickness. Although the method described represents a simple form of providing ventricular assistance, its applicability for long-term circulatory support remains to be evaluated.

Animals↗