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Biomedical subjects

I Klimowicz-Młodzik

Publications and source records attributed to I Klimowicz-Młodzik.

5 recordsLinked to original sources
PubMed1999

[Localization of ischemic lesions in the brain in relation to the main risk factors of stroke].

The aim of the study was the correlation between the risk factors of stroke (arterial hypertension, diabetes mellitus, arrhythmias) and localization of ischemic lesion assessed by CT. The group consisted of 160 patients with ischemic stroke (70 male, 90 female), average age was 62.7 years. The group was divided into the subgroups depending on the localization and extension of ischemic lesion found on CT exam. The first group with cortical-subcortical lesions consisted of 100 patients. The second group with small lesions in deep brain structures consisted of 51 patients. The third consisted of 9 patients with both lesions: cortical subcortical and deep brain structures. 97 patients had history of HTN, 37DM, 47 arrhythmias. Occurrence of HTN was found to be significantly more frequent in the second subgroup. No significant correlation was found between localization of lesion and the diabetes and arrhythmias in remaining subgroups.

Aged↗
PubMed1980

Effect of cerebellar stimulation of hippocampal epileptic discharges in kindling preparation.

The inhibitory effect of cerebellar cortex (Cb) and dentate nucleus (DN) electrical stimulation were studied on 7 cats. After kindling in right hippocampus or in right somato-sensory motor cortex the both Cb and left DN were stimulated monopolarly or bipolarly in each cat. The stimulation was 1 sec train of impulses of 1 ms duration and 60 Hz. The current intensity was 0.3-1.7 mA, 10-12 stimulations were performed in each animal in each structure and the results of stimulations were averaged. The following indices of the stimulation effect were taken into consideration: 1) Number of epileptic spontaneous discharges during 2 min of EEG records before and after stimulation. 2) sum of the epileptic discharges within the periods, 3) time between spontaneous epileptic discharges, 4) time to first paroxysmal discharge after electrical stimulation of the Cb or DN. Results showed prolonged time to the first spontaneous epileptic discharge after stimulation of both structures, thus, indicating statistically significant inhibitory effect of stimulation. The other indices showed no statistically significant inhibitory effects.

Animals↗
PubMedDate not supplied

[Electroencephalographic changes in reversible ischemic cerebral infarction].

In 246 patients with reversible ischaemic neurological deficit eeg investigations were carried out. The eeg curves were compared with the clinical symptoms, with reference to the region of vascularisation, intensity of neurological signs, and time of regression of the clinical symptoms. The obtained results demonstrated, that in 246 EEG records made during acute phase of the disease 110 were normal, and from 136 abnormal records the majority (85 curves) showed only small changes. We have noticed that eeg records with no or small changes we met in patients whose clinical symptoms disappeared during 10 days from the beginning of the disease, where with the neurological syndrome lasting for a longer period, the number of the records with more severe changes was considerably larger. In our opinion, an eeg record showing no, or slight degree of pathology may suggest a reversible character of the ischaemic stroke.

Brain↗
PubMedDate not supplied

[Cigarette smoking and alcohol abuse effects on stroke development].

Cigarette smoking, alcohol abuse and stroke--the material consisted of 272 patients (169 men and 103) women aged between 25-65 years. There were 221 patients with ischemic stroke and 51 patients with haemorrhagic stroke. The control group consisted of 400 healthy subject of the same age and sex. In the stroke group excessive consumption of alcohol was reported by 61 patients (5 women and 56 men). Excessive smoking was reported by 130 patients (41 women and 89 men). It was found in both types of stroke alcohol was not an independent risk factor. In addition, the study revealed that alcohol and cigarette smoking did not increase the risk of developing stroke in patients with diabetes and hypertension. Excessive cigarette smoking was found however, to be an independent risk factor in haemorrhagic stroke.

Adult↗