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Biomedical subjects

I Koncz

Publications and source records attributed to I Koncz.

7 recordsLinked to original sources
PubMed1991

[Congestive gastropathy].

15 patients with congestive gastropathy were reported including clinical and pathological characteristics of the disease. Every patient had alcoholic liver cirrhosis and portal hypertension. 6 patient's stomach was resected while in 2 further cases the disease was found at autopsy. In additional 7 cases the characteristic microvascular changes were observed in endoscopic biopsy specimens from the gastric mucosa. The authors presume that this disease has an acute and a chronic stage. In the acute stage dilated capillaries are present under the surface, not related to the inflammation of gastric mucosa. This phenomenon was described in the literature. In the chronic stage there are dilated and tortuous vessels in the submucosal layer surrounded by collagenous connective tissue. The authors suppose that the thick and fibrotic submucosal layer causes microcirculatory disturbances in the gastric mucosa. The impaired microcirculation may cause extensive ulcers with profuse and sometimes lethal bleeding.

Adult↗
PubMed1989

[Ischemic gastritis--a clinico-pathological entity?].

Eight ulcerative gastroduodenitis are reported in connection with the chronic circulatory disorders. In four patients the severe sclerotic narrowing of splanchnic arteries was proved by autopsies following the operation. Characteristics of chronic ischemic disease of the stomach were as follows: lack of symptoms of chronic peptic ulcus in the previous history; old age; severe pain; sudden losing weight and the ineffectiveness of usual therapy. X-ray, endoscopy as well as intraoperative findings raised the suspicion of a malignant tumour. Authors are of the opinion that chronic ischemic disease of the stomach is an entity pathologically as well as clinically. Histology of the reported cases were compared with 20 chronic peptic ulcers of the stomach and differences were described. Some giant ulcers in old age are suggested belonging to this group of diseases. Practical importance of better knowledge of the ischemic gastritis was emphasized. After recanalisation of the vessels spontaneous healing of gastric ulcers has been reported. Importance of selective arteriography was stressed in cases of gastric ulcers of unusual shape and considerable size.

Aged↗
PubMed1989

Examination of Cavinton effect in elderly diabetic patients.

The effect of Cavinton tablet has been examined in elderly diabetic patients. According to the observations the intellectual performance of the treated patients improved significantly, and their neurological symptoms were moderated as well. The drug did not influence carbohydrate or lipid metabolisms nor did it affect the systemic blood pressure. The results obtained prove that the drug may successfully be used for the treatment of nervous symptoms of elderly diabetic patients. The assure an effective therapy the drug administration has to be started as early as possible--before the development of nervous symptoms. The dosage of the product has to be adjusted individually. Obviously, the currently accepted other drug therapies of manifesting nervous symptoms have to be used as well and the other diseases accompanying advanced age need also be treated.

Aged↗