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Biomedical subjects

I Kron

Publications and source records attributed to I Kron.

14 recordsLinked to original sources

[Plasma renin activity and aldosterone in patients with essential hypertension].

The authors examined the plasma renin activity (PRA) in 80 patients and plasma aldosterone (PA) in 27 patients with essential hypertension (EH). They confirmed the significant drop of stimulated PRA with age. The PA levels of hypertonic patients did not change with age and did not change significantly in relation to PRA. In obese hypertonic patients a satisfactory response of PRA to stimulation was lacking, while PA reacted adequately. The PA levels are thus in older age groups as well as in obese subjects much higher, as compared with relatively low PRA levels. In relation to the stage of EH the authors did not find any significant differences of PRA levels.

Adolescent

[Diagnosis of congenital deficiency of alpha 1-antitrypsin by the immune peroxidase technique (author's transl)].

10 cases of congenital deficiency of alpha 1-antitrypsin with liver involvement were identified on clinical grounds; 10 cases of liver cirrhosis were selected by way of the diastase-PAS-reaction. In these 20 cases alpha 1-antitrypsin was demonstrated in paraffin sections by a modification of the indirect peroxidase-antiperoxidase method. In all these cases the immunoreactive inclusions could be demonstrated in the hepatocytes, even when the paraffin sections were several years old. 399 cases of cirrhosis of the liver were investigated in this retrospective study; only 10 of these cases had, as mentioned above, inclusions in the hepatocytes, which were immunoreactive, PAS-positive, and resistant against diastase.

Adolescent