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Biomedical subjects

I L Martinevskiĭ

Publications and source records attributed to I L Martinevskiĭ.

15 recordsLinked to original sources
PubMed1982

[Trial use of polymyxin and erythromycin for isolating cultures of the plague microbe in the Kyzyl-Kum].

It is recommended that the Hottinger agar medium with polymyxin or erythromycin be used for isolation of pure cultures of the plague microbe from specimens containing various species of microorganisms, except Proteus. Such a procedure was used in the Kizil-Kum for the bacteriological examinations with respect to plague. The procedure may be used in the natural foci with the strains resistant to these antibiotics.

Animals↗
PubMed1981

[Response, to polymyxin, of plague microbe strains isolated from various natural foci and of their mutants with a decreased requirement in nutritional factors].

Investigation of the response to polymyxin of 65 strains of Pasteurella isolated from various foci and 46 their back mutants showed that all of them were usually highly resistant to polymyxin (MIC 200--500 micrograms/ml). The Pasteurella strains isolated in the Gissaro-Darvaz natural focus, Turkey and Congo were highly sensitive to polymyxin (MIC 10--25 micrograms/ml). Single cultures highly sensitive to the antibiotic were detected among the polymyxin-resistant strains. Polymyxin-sensitive mutants of these cultures with lowered requirements in the growth factors were obtained.

Brazil↗
PubMed1979

[Proline-dependent wild strains and proline-dependent mutants of the plague microbe].

It is found that the growth of Yersinia pestis wild strains, isolated from Citellus musicus Menetrié in the Central Caucasus, depends on the presence of proline in the medium. Proline can not be substituted by glutamic acid, other amino acids or vitamins. 28 proline-requiring mutants were selected from Y. pestis marmot strain 20b. Three groups of proline-requiring Y. pestis mutants are established, similar to those of Escherichia coli. The requirement of proline does not affect the virulency, pigment formation and calcium dependence.

Animals↗
PubMed1975

[Bacteriocinogeny in Yersinia enterocolitica].

Bacteriocinogeny was found in 19.8 per cent of Y. enterocolitica strains tested. It was designated by the authors as enterocoliticacinogeny and the substance produced by the pathogen was named enterocoliticacine. Bacteriocinogeny was found among the collection strains isolated in the South Primorye and not among the strains isolated abroad. Some cultures of Y. enterocolitica isolated abroad and in the South Primorye were used as indicator strains for revealing enterocoliticacinogeny. Enterocoliticacine inhibited growth only of some strains of Y. enterocolitica and had no inhibitory effect on growth of Coli bacteria, plague and pseudotuberculosis microbes. The latter 3 bacterial species did not inhibit growth of the causative agent of gastric yearsiniosis, which may be of some diagnostic importance. The diverse spectrum of enterocoliticacine and the character of inhibition of sensitive culture growth are indicative of the presence of several types of bacteriocines in Y. enterocolitica.

Animals↗
PubMed1975

[Isolation and properties of several auxotrophic mutants of a highly virulent strain of the plague microbe].

2432 stable auxotrophic mutants were selected from high virulent Yersinia pestis strain 20b after treatment with nitroso guanidine. They were deficient in amino acids (arginine, aspartic acid, citrulline, glycine, glutamic acid, histidine, isoleucine, serine, leucine, lysine, ornithine, proline, tryptophan, tyrosine, valiney, pyrimidine and vitamins (riboflavin, thyamine, nicotinamide). Some mutants were two- and three-fold dependent. The leucine-, histidine-, purine-dependent mutants were isolated with the high frequency. All the mutants, like their original strain, grew in R-form; they were sensitive to diagnostic phages, had pesticine-fibrinolysin-coagulase sustem (fraction I) and were calcium-dependent. P+ cultures of auxotrophs were not virulent for laboratory animals.

Animals↗
PubMed1975

[Isolation and properties of several auxotrophic mutants of a highly virulent strain of the plague microbe].

2432 stable auxotrophic mutants were selected from high virulent Yersinia pestis strain 20b after treatment with nitroso guanidine. They were deficient in amino acids (arginine, aspartic acid, citrulline, glycine, glutamic acid, histidine, isoleucine, serine, leucine, lysine, ornithine, proline, tryptophan, tyrosine, valine), pyrimidine and vitamins (riboflavin, thyamine, nicotinamide). Some mutants were two- and three-fold dependent. The leucine-, histidine-, purine-dependent mutants were isolated with the high frequency. All the mutants, like their original strain, grew in R-form; they were sensitive to diagnostic phages, had pesticine-fibrinolysin-coagulase system (fraction I) and were calcium-dependent. P+ cultures of auxotrophs were not virulent for laboratory animals.

Amino Acids↗
PubMed1975

[Intestinal yersiniasis in the Far East. The sensitivity and cross resistance to antibiotics of Yersinia enterocolitica strains isolated in the Maritime Territory].

The author studied 121 strains of Yersinia enterocolitica isolated in the Ptimorye Territory. It was found that by their sensitivity to antibiotics the strains did not differ from the analogues abroad strains: they were highly sensitive to tetracycline, streptomycin, kanamycin, neomycin and monomycin (MIC 1.25 to 0.6 gamma/ml or units/ml), less sensitive to oxytetracycline, chlortetracycline, levomycetin, oletetrine and gramicidine (MIC 10-5 gamma/ml), highly resistant to penicillin (MIC 100-50 gamma/ml), erythromycin and polymyxin (MIC 500-100 gamma/ml). No differences in the sensitivity to the above antibiotics of the Far East strains as dependent on the place period and source of isolation and inidentity of their biochemical characteristics were found. Cross resistance in Yersinia enterocolitica forms with artificially developed resistance to some antibiotics was found. No cross resistance with tetracycline was noted in the streptomycin resistant variants of the bacteria.

Anti-Bacterial Agents↗
PubMedDate not supplied

[The distribution of fleas of the genus Xenopsylla in the Ustyurt].

The distribution areas of the main plague vectors of Xenopsylla fleas (X. skrjabini, X. gerbilli, X. nuttalli) in the Ustyurt are given for the first time. They are found to be of great practical significance in the evaluation of the epizootic situation.

Animals↗