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Biomedical subjects

I Loureiro

Publications and source records attributed to I Loureiro.

3 recordsLinked to original sources
PubMed1993

Influence of stress on IgE production.

Intense acute stress, consequent to restraint, leads to a diminished production of IgE antiovalbumin antibodies in mice. The IgE content of sera from experimental or control animals was assayed by the enzyme-linked immunosorbent assay (ELISA) at days 8, 16, and 20 after immunization. The statistics revealed significant differences in the IgE level of the animals submitted to acute stress and home cage control animals on days 16 and 20 after immunization, but not on day 8.

Anaphylaxis↗
PubMed1993

Decrease in passive cutaneous anaphylaxis reactions in rats secondary to stress.

Anaphylaxis was assayed by the passive cutaneous anaphylaxis (PCA) test in male Wistar rats (250 g body weight). Three experimental groups were used: animals restrained in an electric chamber and submitted to electric shock immediately after sensitization and 24 h before anaphylaxis (31 animals), animals restrained in the electric chamber for the same time but receiving no electric shock (23 animals), and non-manipulated, home-cage control animals (24 animals). The frequency of PCA reactions was decreased in the group of animals submitted to restraint when compared with the home-cage control group. However, the group of animals submitted to both restraint and electric shock showed no decrease in the frequency of PCA reactions. It is suggested that, in rats, stress induced by restraint decreases PCA reactions and that this decrease is counteracted by a simultaneous stress induced by electric shock.

Animals↗