Biomedical subjects
Publications and source records attributed to I Loyber.
Bilateral lesion of the anterodorsalis thalami nucleus produces a significant increase in corticosterone concentrations in plasma and adrenal tissue. In contrast, adrenal catecholamines decrease in response to the lesion.
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The circulating levels of total thyroxine (T4) and normalized thyroxine (T4N) were studied in 41 institutionalized children (IC) and in 22 control children (CC), from two to six years old. No difference were observed in the values of T4 between the two groups but in IC, T4N levels are inferior to those in CC. The periods children have been confined, their chronological age and their age at the time of admittance greatly influence these results. The differences between IC and CC become important in the IC groups with less than 6 months of confinement and with more than 24 months, in the groups of 4-year-old children and in the ones admitted before 1 year of age or after 4 years of age. In all parameters studied, the differences with CC in girls are more significant than in boys.
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The object of this investigation is to study effects of bulbectomy on female rats operated on at 15 and 30 days of age (prepubescent), 50 days (pubescent) and 120 days (adult), with respect to various parameters: these comprise corporal weight, liver weight, blood sugar, liver glycogen, glucose tolerance test and serum free fatty acid. Results were as follows. Body weight: in all groups this was significantly less than in controls except for rats operated on at adult age. Liver weight: (% of body weight) decreases in all groups, but significantly only in animals operated on when 15 days old. Blood sugar: significantly lessened in rats operated on when 30 and 120 days old. Liver glycogen: lessens in rats operated on at 30 and 120 days of age, but significantly only in the former. Glucose tolerance test: the coefficient k is found to increase in rats operated on at 15, 30 and 120 days of age; there is a significant increase in the first two groups. Serum free fatty acids: no marked alterations in any of the groups.
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