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Biomedical subjects

I Lukác

Publications and source records attributed to I Lukác.

11 recordsLinked to original sources
PubMed2006

Carbon tetrachloride as a thermoporometry liquid probe to study the cross-linking of styrene copolymer networks.

Mesh size distributions (MSDs) of swollen cross-linked styrene copolymer networks have been measured by thermoporometry using CCl(4) as a probe liquid. All numerical relationships required for the calculation of the MSD were established for both the liquid-to-solid and the solid-to-solid thermal transitions of CCl(4) and successfully validated on test samples. It was found that the polymer network, for both thermally and photo-cross-linked materials, was completely built in about 4 h of exposure. A clear correlation was established between the average mesh size of the swollen polymer network on one hand and the benzoyl peroxide groups content and swelling ratio on the other hand.

Algorithms↗
PubMed2005

Experimental cauda equina compression induces HSP70 synthesis in dog.

The heat shock protein 70 (HSP70) is a key component of the stress response induced by various noxious conditions such as heat, oxygen stress, trauma and infection. In present study we have assessed the consequences of the compression of lower lumbar and sacral nerve roots caused by a multiple cauda equina constrictions (MCEC) on HSP70 immunoreactivity (HSP70-IR) in the dog. Our data indicate that constriction of central processes evokes HSP70 up-regulation in the spinal cord (L7, S1-Co3) as well as in the corresponding dorsal root ganglion cells (DRGs) (L7-S1) two days following injury. A limited number of bipolar or triangular HSP-IR neurons were found in the lateral collateral pathway (LCP) as well as in the pericentral region (lamina X) of the spinal cord. In contrast, a high number of HSP70 exhibiting motoneurons with fine processes appeared in the ventral horn (laminae VIII-IX) of lumbosacral segments. Concomitantly, close to them a few lightly HSP70-positive neuronal somata or cell bodies lacking the HSP70-IR occurred. In the DRGs, HSP70 expression was mildly up-regulated in small and medium-sized neurons and in satellite cells. On the contrary, DRGs from intact or sham-operated dogs did not reveal HSP70 specific neuronal staining. In conclusion, we have demonstrated that the MCEC in dogs mimicking the cauda equina syndrome in clinical settings evokes expression of HSP70 synthesis in specific neurons of the lumbo-sacro-coccygeal spinal cord segments and in small and medium sized neurons of corresponding DRGs. This suggests that HSP70 may play an active role in neuroprotective processes partly by maintaining intracellular protein integrity and preventing the neuronal degeneration in this experimental paradigm.

Animals↗
PubMed2005

[Prevention of the anastomosis dehiscence following low anterior rectal resections].

Authors analyse 106 patients that were operated in their department by Dixon's method, in retrospective study. They analyse indications for operations, lesions distance in rectum, endosonographic and CT findings. Basic principles of the operation technique are adequate blood flow, sufficient colon mobilization and tightness of the anastomosis being supplemented with transanal pertubation. Out of early complications anastomosis dehiscence appeared in 6 patients (e.g. 5.6%) out of which 4 were treated conservatively and 2 were being reoperated on (by axial ileostomia and drainage). In discussion different opinions on preoperative preparation, neoadjuvant therapy, presacral drainage, transanal pertubation and other decompressive techniques are anticipated.

Adult↗
PubMed2005

[Giant retroperitoneal liposarcomas].

According to literature liposarcomas account to less than 0.1% of all human tumors, 13% of which are localiced retroperitoneally. Authors describe two cases of giant retroperitoneal liposarcoms treated in their department. CT findings and the course of the disease discussed. Conlusively authors remark of high probability of microscopical residual disease with need of patients' follow up with eventual reoperation and adjuvant radiotherapy.

Aged↗
PubMed2001

Effect of spinal cord compression on cyclic 3',5'-guanosine monophosphate in the white matter columns of rabbit.

Changes in the level of cyclic 3',5'-guanosine monophosphate (cGMP) were studied one day after a surgically induced spinal cord constriction performed at the Th7 segment level in the dorsal, lateral and ventral white matter columns and in the non-compartmentalized white matter of Th5-Th6 segments, i.e., above the site of the spinal cord constriction and in Th8-Th9 segments, located below the spinal cord constriction. The midthoracic spinal cord constriction caused a significant decrease in the level of cGMP in the ventral column of Th5-Th6 segments and a significant increase in the lateral column of Th8-Th9 segments. The level of cGMP in the dorsal column, located either rostrally or caudally to the site of the spinal cord injury, remained unchanged. In addition, no significant changes in the level of cGMP were found in the non-compartmentalized white matter of Th5-Th6 and Th8-Th9 segments in response to constriction of the Th7 segment.

Animals↗
PubMed2001

[A "dumbell" tumor of the mediastinum--case report].

Tumours situated in the posterior mediastinum and spreading to the spinal canal via the intervertebral opening are described as "dumbbell" tumours. The authors submit the case-history of a 44-year-old patient admitted to the Second Surgical Clinic Pasteur Faculty Hospital, Safarík University Kosice after repeated laminectomy and extirpation of the intraspinally spreading part of a mediastinal tumour. The mediastinal part of the tumour was removed surgically, the histological result was described as a melanotic schwannoma. The postoperative course was without complications, the patient was discharged home in a good condition on the 8th day after the operation. In the conclusion the authors emphasize the necessity to remove the tumour in toto. A one-stage operation in collaboration with a neurosurgeon seems appropriate.

Adult↗
PubMed1995

[Obstructive ileus--a complication of laparoscopic cholecystectomy].

A 45-year old patient admitted with confirmed calculous pancreatitis underwent the laparoscopic cholecystectomy at the 14th day of the hospitalization. 4 days after the operation he had to be reoperated due to small-bowel-obstruction caused by the herniation of the loop through the supraumbilical port. The small bowel was reduced and plasty of the operative wound was done. Postoperative course was uncomplicated and the patient was discharged from the hospital 6 days after the operation.

Cholecystectomy, Laparoscopic↗
PubMed1994

[Personal experience with laparoscopic cholecystectomy].

During the period of 29 months the first 100 laparoscopic cholecystectomies were performed at the Department of Surgery of the Ruzinov Hospital in Bratislava. There were 79 women and 21 men with mean age of 41.5 years (16-67). All operations were modified by the use of only 3 incisions. In 2 patients were the operations converted to open colecystectomy because of perforation of gallbladder in 1 patient because of bleeding. The average operating time was 99.1 minutes (35-225). Intraoperative cholangiography was not carried out in any patient. 2 patients were reoperated because of slipping of the clips from ductus cysticus and 1 patient because of hernia in a scar. All laparoscopic cholecystectomies were planned. The average hospital stay was 5.8 days (3-12). There was no death in our series.

Adolescent↗
PubMed1991

[Hemophilia from the viewpoint of the neurosurgeon].

The authors describe a case of cerebral haemorrhage associated with haemophilia A--their own observation, findings and confrontation with data in the literature. They draw attention to the rare incidence of the above complication, discuss the site of haemorrhage and possibilities of treatment.

Adult↗
PubMed1988

Chronic extradural haematoma of the posterior fossa. Case report.

The authors present the case of extradural haematoma of the posterior fossa in a four-year-old boy who was successfully operated on seventeen days after he had suffered a blow on his occiput. Emphasis is placed on the importance of an early CT scan in a patient showing any clinical signs of possible intracranial pathology following such injury.

Brain Concussion↗