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Biomedical subjects

I M Crosato

Publications and source records attributed to I M Crosato.

4 recordsLinked to original sources
PubMed1993

[Solid tumors associated with HIV infection].

Between December 1986 and December 1991, the Italian Cooperative Group on AIDS-related tumours documented 94 HIV related solid tumours. Of 21 germinal testicular tumours collected, ten were seminomas. Cervical carcinoma was observed observed in 28 IVDAs (intraepithelial in 8 and advanced, with rapid progression, in one). Lung cancer associated with HIV infection was reported in 14 patients. Also reported were two cases of colorectal carcinoma, one anorectal carcinoma, one pancreatic carcinoma, one carcinoid, one oral carcinoma. Of the central nervous system tumours, were diagnosed 3 cases of glioblastomas, one medulloblastoma and one meningioma. This retrospective study shows that while oral and anorectal tumours were very rarely observed, a wide spectrum of other HIV-related solid tumours were found in this series. The required therapeutic approaches may not necessarily be influenced by the HIV infection, in contrast with the observed pattern for treatment of EKS and lymphomas in HIV infected subjects.

Adult↗
PubMed1990

Nasopharyngeal lymphatic tissue in patients infected with human immunodeficiency virus. A prospective clinicopathologic study.

A prospective clinicopathologic study of the nasopharyngeal lymphatic tissue, using a standardized approach, was carried out in 66 patients infected with human immunodeficiency virus (HIV) in Aviano, Italy. Two hundred eighteen patients without HIV infection served as a control group. A significantly higher percentage of nasopharyngeal lymphatic tissue hypertrophy was observed in HIV-infected patients compared with the control group, both clinically and pathologically. The finding of a higher incidence of nasopharyngeal lymphatic tissue hypertrophy during some stages of the disease, when cervical lymph nodes are enlarged, suggests that the extranodal nasopharyngeal district behaves in the same way as the lymph nodes. Nasopharyngeal lymphatic tissue hypertrophy should be placed at the forefront of the hitherto known head and neck manifestations of HIV infection. An ear, nose, and throat examination is mandatory for all patients with known or suspected HIV infection.

AIDS-Related Complex↗
PubMedDate not supplied

[Role of the otorhinolaryngologist in HIV infections].

The spreading of HIV infection and the importance of otorhinolaryngological examination in serum positive patients has given rise to some literature regarding the E.N.T. manifestations of this infection. In particular these works underline the nasopharyngeal lymphatic tissue hypertrophy (NLTH). The present work reports data drawn from two years of experience with 69 HIV patients most of which were intravenous drug users (IVDU). The nasopharyngeal findings, divided into 4 classes both in regard to clinical and anatomopathological characteristics, showed that there was a higher incidence of NLTH in HIV+ patients than in the control group. NLTH was particularly found during the initial stages of the disease, in patients ranging in age from 20 to 29 and in IVDU. The most common manifestations found both in the 69 patients examined and in the literature are listed and the main clinical aspects of the various stages of the disease, from contacting AIDS are dealt with. The peculiarity of NLTH is discussed and a viral etiology is suggested even though further study is required to better clarify the physiopathology of the nasopharyngeal lymphatic tissue during an HIV infection. Finally, the importance of a thorough examination of the initial portion of the aerodigestive tract is stressed in all HIV+ cases.

Acquired Immunodeficiency Syndrome↗