Biomedical subjects
Publications and source records attributed to I M Fox.
The diagnosis of bone infection in the patient with nonvirgin bone is a diagnostic dilemma. This is especially true in the diabetic patient with a soft tissue infection and an underlying osteoarthropathy. The authors present a retrospective study using the new scintigraphic technique of indium-111-labeled white blood cells as a method of attempting to solve this diagnostic dilemma.
A double-stemmed MTP joint silastic implant has been described that acts as a flexible spacer for a number of pathologic conditions that affect the lesser metatarsophalangeal joints. Preliminary results suggest that this is a feasible alternative to joint destructive procedures with advantages over previously described implants.
Osteochondritis dissecans of the talus is a well documented entity, defined as a transchondral fracture of the dome of the talus. As a fracture, it should heal with immobilization; however, this lesion often causes severe disability and, more often than not, the fragment will not unite with conservative treatment. There is much debate concerning operative versus nonoperative treatment, and the purpose of this paper is to discuss the salient points of the controversy, review literature on the subject, and present a case with a follow-up of 4.5 years.
Intraosseous lipoma is a very rare bony tumor. Most of the documented reports are isolated cases, and in the foot all are limited to the calcaneus. This manuscript presents a case of an intraosseous lipoma of the fifth metatarsal. The radiologic and pathologic features of the lesion are described.
The diagnosis of osteomyelitis in the presence of soft tissue infection and neuropathic bone changes is often difficult in the diabetic foot. Previous attempts at scintigraphic diagnosis included Tc-99m methylene diphosphonate, Gallium-67 citrate and Indium-111 autologous leukocytes (WBCs). A new agent recently available, Technetium-99m-HMPAO labeled white blood cells, shows promise as a scintigraphic agent superior to other agents for this purpose. The authors discuss this agent and present a case report as a preliminary study.