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Biomedical subjects

I M Frolov

Publications and source records attributed to I M Frolov.

12 recordsLinked to original sources

["Interventional radiology" in breast examination].

The data on such highly-effective invasive diagnostico-therapeutic procedures as ductography, sclerosing-solution cystography, X-ray-controled puncture biopsy, stereotactical computer technique, sonography and preoperative maging of nonpalpable lesions were analyzed following a complex mammographic examination of 20,000 patients with different breast pathologies. Advantages offered by complex breast examination are discussed. Among them were the use of optimal effects of each invasive procedure, an accuracy of preoperative diagnosis reaching 95-98% (nonpalpable breast lesions included) and a significantly reduced extent of breast surgery.

Adult↗

[Invasive methods in complex radiologic diagnosis of breast diseases].

The report deals with such present-day invasive procedures of breast examination as X-ray-controlled puncture, puncture using X-ray contrast, Cytoguide video-accessory unit controlled puncture biopsy, "pistol-needle" application, ultrasound aiming puncture, pneumocystography, ductography and preoperative interstitial marking of nonpalpable masses. If latest invasive procedures are used during complex examination of the breast, diagnostic accuracy can be raised to 95-97%.

Adult↗

[Differential diagnosis of circumscribed growing breast tumors].

The results of a comparison of clinical, roentgenological and cytological investigation of circumscribed growing tumours of the breast are reported - 43 carcinomas and 19 intracanalicular fibroadenomas - that are hard to differentiate. A number of diagnostically valuable symptoms are described: Significant for carcinoma are an age over 55, microcalcifications (60 +/- 13% of the cases) and different sizes of the tumour found by palpation and mammography (35 +/- 9% of the cases). The diagnostic accuracy of the methods was: clinical 44 +/- 8%, roentgenological 79 +/- 7%, cytological 89 +/- 3% and for their joint application in a special mammographic cabinet 98 +/- 2%.

Adult↗

[Intervention studies in breast diseases].

Based on results of comprehensive examination of 20,000 females with different breast diseases in a specialized mammological room, the paper presents the most informative invasive techniques that combine diagnostic and therapeutical potentialities, such as ductography, cystography using various sclerosing solution, various types of needle biopsies under X-ray guidance, stereotactic computer devices, ultrasound study, and various labeling modes for nonpalpable formation before surgery. It shows in expedient to make a comprehensive examination under the conditions of a mammological room where the advantages of this or that invisable intervention, including those without a dosage load, are rationally, without duplicating, used depending on the diseases detected, which increases the significance of preoperative diagnosis up to 95-98%, including that of nonpalpable formations by substantially reducing the proportion of surgical interventions into the breast.

Adult↗

[Differential diagnosis of breast tumors with limited growth].

The paper is concerned with the results of comparative analysis of the clinical, x-ray and cytological methods of investigation of women with breast tumors in situ (43 cases of cancer and 19 cases of intracanalicular fibroadenoma, the latter being difficult for differential diagnosis). A number of important diagnostic symptoms were identified. Cancer affected more frequently women over 55. It was characterized by the presence of microcalcinates (60 +/- 13%) and inadequacy of tumor sizes on palpation and on radiograms (35 +/- 7%). The diagnostic accuracy of the methods used separately was 44 +/- 8% for the clinical method, 79 +/- 7% for the x-ray method, and 89 +/- 3% for the cytological method. Their combined use in a specialized mammography unit resulted in 98 +/- 2% of diagnostic accuracy.

Adult↗

[Contemporary methods of the target puncture of the mammary gland].

New accurate methods of puncture of the mammary gland, making use of preliminary layout using roentgenograms, coordination nets, Cytoguide comprter device, and ultrasound-monitored spot biopsy replaced the traditional poorly informative methods. Sonography-monitored puncture is the most informative in cases with both palpated and unpalpated formations shaped as nodules: it permits imaging in 85% of cases. However, in 25-30% of cases unpalpated cancer presents as microcalcinates and cord-like restructuring which cannot be imaged on sonograms. Moreover, unpalpated cancer presenting as a nodule against the background of fatty involution also may be undiscernible on sonograms. In such cases puncture controlled by roentgenography with a computer device and a relevant kit of disposable instruments is advisable, giving accurate information in 61.1% of cases.

Adult↗

[Possibilities of various diagnostic methods in the assessment of the state of axillary lymph nodes in breast cancer].

The incidence of axillary lymph nodal metastases in breast cancer is proportional to the size of a focus: To is 25 +/- 25%, T1-33 +/- 17%, T2-55 +/- 7%, T3-65 +/- 11%, the choice of the optimum treatment regimen requires more accurate preoperative detection of metastatic lymph nodes. Ultrasound technique (its accuracy is 80%, sensitivity-88%) is of the most diagnostic value in the detection of metastatic lymph nodes. The absence of echographic signs supports the nonspecific nature of changes. Palpation is preferable in nonspecific axillary lymph nodal lesions. The status of axillary lymph nodes in breast cancer may be correctly assessed by comprehensive clinical and ultrasonic studies of the axillary area wherein, supplementing each other, each technique yield the maximum information.

Adult↗

[Differential radiation diagnosis of microcalcinates grouped in breast].

A complex methods was used to examine 39 females with the microcalcinates grouped in the breast. The diagnostic efficiency of a number of mammographic and sonographic signs was comparatively evaluated. Ultrasonography was shown to be advisable in differentially diagnosing cancer and sclerosing adenosis. A combination of mammography and sonography may establish an accurate diagnosis in 78% of cases.

Adult↗