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Biomedical subjects

I M Gandzha

Publications and source records attributed to I M Gandzha.

At least 19 recordsLinked to original sources
PubMed1993

[The level of serum thymic activity in patients with rheumatoid arthritis and systemic lupus erythematosus].

Thymic serum activity (TSA) has been studied in 52 healthy subjects, 48 rheumatoid arthritis patients and 17 sufferers with systemic lupus erythematosus aged from 18 to 70. TSA was compared in patients under and over 40 years. In those under 40 TSA appeared significantly inhibited, while in older subjects it did not differ from age-matched control. No correlations were reported between TSA levels and clinical characteristics. Changes in TSA levels may be related both to low content of thymic hormones and formation of inactive complexes from thymic mediators with inhibitors.

Adolescent↗
PubMed1990

[The levels of circulating immune complexes and immunoglobulins in patients with systemic lupus erythematosus and rheumatoid arthritis].

UNLABELLED: The authors studied the levels of large- and medium molecular circulating immune complexes (CIC) and immunoglobulins of main classes (Ig) in 17 patients with systemic lupus erythematosus (SLE) and 47 patients with rheumatoid arthritis (RA). RESULTS: low molecular CIC increased in 35.2% of patients with SLE and in 42.5% with RA; patients with SLE showed a significant reduction of IgA in 80.4%. The IgA/IgM ratio was significantly reduced in SLE due to the above finding. The IgA level remained unchanged in RA.

Adolescent↗
PubMed1989

[The etiology and pathogenesis of dilated cardiomyopathy].

The authors analyze cardiomyopathies as primary lesions of the heart of unknown etiology. Examination of skin biopsies in patients with dilated cardiomyopathy indicates the presence of morphological signs of the systemic character of the process in the connective tissue, an increased content of circulating immune complexes in the blood of patients. In hypertrophic cardiomyopathy similar changes were found only in one patient. Dilated cardiomyopathy is a manifestation of a systemic immunopathological process in most of these patients.

Adolescent↗