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Biomedical subjects

I M Mendeleev

Publications and source records attributed to I M Mendeleev.

12 recordsLinked to original sources

[A severe course of autoimmune thrombocytopenia and the procedure for its treatment in systemic lupus erythematosus].

The authors describe three comparatively rare cases of extremely severe symptomatic autoimmune thrombocytopenia associated with systemic lupus erythematosus. The use of glucocorticoids in large doses and in two cases of splenectomy turned out ineffective. The next therapeutic measures are suggested in the following succession: glucocorticoids----cytostatic drugs (vincristine)----splenectomy to be performed only in special cases.

Acute Disease

[Results of 16-year use of the 06-Paris-LA-66 program in the treatment of children with acute lymphoblastic leukemia].

The treatment of children with acute lymphoblastic leukemia was conducted with the use of 06-Paris-LA-66 program modified by the authors. Complete remission was obtained in 91.8% of cases. Recovery was achieved and the therapy was discontinued in 16 out of 34 patients who had strictly adhered the program treatment, the treatment of 7 patients in complete remission is continued. The authors consider the program as high efficient and recommend its use.

Adolescent

[The efficacy of treatment using expanded programs of megavolt irradiation and polychemotherapy in patients with lymphogranulomatosis in stages I, II and IIIA].

The authors relate the results of multimodality treatment of 90 patients with stages I-IIIA lymphogranulomatosis. The total survival amounted to 86.4 +/- 3.8% within the time exceeding 7 years. The efficacy of the treatment of patients with lymphogranulomatosis of different stages by using multi-beam and broad-beam radiation is under comparison. The data obtained indicate that total radiation of lymph nodes in patients with stage II lymphogranulomatosis is not advisable.

Antineoplastic Combined Chemotherapy Protocols