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Biomedical subjects

I M Robertson

Publications and source records attributed to I M Robertson.

7 recordsLinked to original sources

Anetoderma of prematurity in association with electrocardiographic electrodes.

Anetoderma in premature infants is an uncommon lesion that may be associated with the use of various types of monitoring leads. In 2 infants multiple papules of anetoderma occurred on the forehead in association with the use of gel electrocardiographic electrodes. It is postulated that the cause of these papules was a local hypoxemia caused by pressure from the electrodes. Growth-restricted infants may be particularly predisposed to iatrogenic anetoderma.

Biopsy, Needle↗

Controlled environment transmission electron microscopy.

The design of a controlled environment electron microscope is described and examples are presented to demonstrate the information that can be obtained by studying gas-solid interactions in real time and at high spatial resolution.

Environment, Controlled↗

Benign hypergammaglobulinaemic purpura of Waldenström associated with lymphoid interstitial pneumonitis.

A 31-year-old female is described who developed benign hypergammaglobulinaemic purpura and lymphoid interstitial pneumonitis concomitantly. High titre anti-nuclear antibodies were also noted. Several years previously, the patient had developed myasthenia gravis and multiple sclerosis. The present case is an example of multiple medical disorders characterized by immune dysregulation and represents the first reported associated of hypergammaglobulinaemic purpura with lymphoid interstitial pneumonitis.

Adult↗

Acquired ichthyosis in bone marrow transplant recipients.

BACKGROUND: Acquired ichthyosis (AI) has been described in a variety of clinical situations. We have observed cases of ichthyosis in bone marrow transplant recipients. OBJECTIVE: Our purpose was to characterize these changes clinically and histologically and to compare them with other cases of acquired ichthyosis. METHODS: Skin biopsy specimens were taken before transplantation and from affected areas after transplantation. RESULTS: AI was observed in four patients who had received a bone marrow transplant for leukemia. None of the patients had a previous personal or family history of ichthyosis. In all patients graft-versus-host disease developed after transplantation. The eruption clinically and histologically most closely resembled ichthyosis vulgaris. The ichthyotic changes appeared to be unrelated to specific drug therapy. CONCLUSION: AI is a previously unreported cutaneous complication of bone marrow transplantation. It may be related to graft-versus-host disease in these patients.

Acute Disease↗

Pityriasis rosea-like eruption after bone marrow transplantation.

Bone marrow transplantation is associated with numerous cutaneous complications that may be related to the underlying (preexisting) disease, to pretransplant conditioning, to immunosuppression, to concomitant medication, or to graft-versus-host reaction. We describe four bone marrow transplant recipients with the clinical and histologic features of pityriasis rosea, a hitherto unreported association.

Adult↗