[Fever-reducing therapy in childhood with NSAID].
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Biomedical subjects
Publications and source records attributed to I Marosvári.
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Eight cases are reported here. Isolated Penicillin resistant Streptococcus pneumoniae strains were also resistant to Oxacillin, Erythromycin, Ampicillin, Cotrimoxazole. In five cases resistance to second generation cephalosporines (Cefaclor, Cefuroxime) also could be demonstrated. All of these multiply resistant strains retained their susceptibility to the third generation cephalosporines (Cefotaxime, Ceftriaxone). Claforan treatment resulted recovery in all of the patients.
The authors report about two cases of AIDS in infancy. Both infants were Rumanian citizen brought to Hungary for examinations. Hepatosplenomegaly, lymphadenopathy and recurrent upper respiratory tract infections respectively were the main clinical symptoms. The infections seemed to have nosocomical origin. Patients coming from Rumania are belonging to the high risk group as to the carrier state. Regular screening before or during hospital admission is advised therefore.
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Staphylococcus saprophyticus was cultured from the urine of a pyelonephritic newborn as well as a 13 years old boy with symptoms of low urinary tract infection. Cefotaxime respectively Penicillin treatment resulted cure in both cases. Staphylococcus saprophyticus may be an important infective agent in children's urinary infections as well.
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The effect of flumecinolone, a new drug with enzyme inductor properties, on non-haemolytic hyperbilirubinaemia of term and premature newborns has been investigated. Prophylactic treatment with the drug prevented the development of severe hyperbilirubinaemia. Alone or in combination with phototherapy, flumecinolone inhibited the steep rise of serum bilirubin in premature infants. A similar effect has been shown in term babies with haematomas. The new drug is void of all side-effects of phenobarbital.
In newborn twins at three hours of age adrenal calcification has been detected. In addition to hepatomegaly, vomiting and diarrhoea, characteristic radiological findings confirmed the diagnosis of the rare heritable lipidosis, Wolman's disease.
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Haemocarboperfusion was used with success in two cases for the treatment of hyperbilirubinaemia of newborns with haemolytic disease. The method will be useful in the lack of the necessary amount of blood for exchange transfusion and will successfully prevent the CNS damage.