Biomedical subjects
I Marsh
Publications and source records attributed to I Marsh.
'Salvage atherectomy' for discrete arterial dissections resulting from balloon angioplasty.
OBJECTIVE: To review the outcome of attempted salvage atherectomy performed following failed balloon angioplasty at a single centre. DESIGN: Retrospective study. PATIENTS: All patients undergoing percutaneous directional atherectomy shortly after failed coronary or peripheral balloon angioplasty at St Paul's Hospital, Vancouver, British Columbia, are reported. INTERVENTIONS: Salvage atherectomy was performed in six patients following failed balloon angioplasty prior to hospital discharge. In each case, a discrete mural flap resulted in a compromised lumen and ischemia. MAIN RESULTS: Percutaneous directional atherectomy successfully recovered atheromatous intimal fragments with restoration of arterial patency in all patients. Media was identified in one specimen and adventitia in none. Perforation did not occur and there were no complications. One patient had documented restenosis and a second had a significant lesion at a more proximal site with a follow-up of four to 15 months (mean nine). Both patients underwent uncomplicated repeat balloon angioplasty without angiographical dissection. CONCLUSIONS: Salvage atherectomy has a limited--but still useful--role in the management of discrete, obstructive arterial dissection flaps complicating balloon angioplasty.
TOXBASE: a microcomputer database for post mortem toxicology.
A cheap microcomputer program for the storage, retrieval, and analysis of the results of toxicological investigations on samples obtained at necropsy was devised. The program was written using FoxBASE+, a dBase III clone, which is both cheaper and faster than other comparable software. The hardware requirements are an IBM PC compatible microcomputer, preferably with both hard and floppy disc drives, and a suitable printer. The system was found to be particularly useful when preparing reports for coroners and in retrieving data for administrators concerned with aspects of work in the laboratory. The system is flexible and can be readily adapted to other uses.
Fatal temazepam overdoses.
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The bilary excretion of flavanones in the rat.
1. The major biliary metabolites of flavanones in the rat have been identified by chromatographic and spectral methods. 2. Evidence is presented that flavanones and flavanone glycosides, following oral or parenteral administration, undergo glucuronylation and are selectively excreted via the bile. 3. Flavanone glycosides but not unconjugated aglycones may be excreted to a significant extent in bile. 4. The percentage of parenterally administered flavanones excreted in bile varies inversely with the amount administered.
The GP's task: educational objectives.
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A rapidly fatal overdose with flecainide.
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Focusing on solutions.
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