Experimental allergic encephalomyelitis (EAE)-changes in structure and proliferation in rat lymph nodes after sensitization with guinea-pig and bovine basic myelin protein.
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Publications and source records attributed to I Matous-Malbohan.
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Dexamethasone, when administered from day 0 to day 9 following the sensitizing injection of encephalitogenic protein in complete Freund's adjuvant, suppressed both the characteristic enlargement of the paracortical area of the draining lymph node and the development of clinical and histopathological signs of experimental allergic encephalomyelitis. Division of cells within the node was not inhibited and therefore the effect of dexamethasone appeared to be a consequence of reduced migration of lymphocytes into the node.