A possible link between the pulmonary and urinary tract IgA response.
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Biomedical subjects
Publications and source records attributed to I Mattsby.
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Three cases of humidifier fever were detected in an office environment. Flavobacteria were found in the contaminated water in a humidifier. After an experimental exposure, the three persons with previous symptoms suffered from fever and slight respiratory symptoms. A leucocytosis and an increase in the number of segmented white blood cells were found the day following the exposure. General immunoglobulins as well as antibodies to Flavobacterium and endotoxin were slightly elevated in the exposed group. The possibility that endotoxins may be the causative agent by means of an indirect complement activation is discussed.
A clinical investigation was made between workers exposed to dried sewage sludge dust and age matched controls not exposed. About 50% of the workers reported work related fever, eye symptoms and general fatigue. Thirteen percent of the workers in the sewage plant reported work related diarrhea. Serum immunoglobulins, white blood cells and thrombocytes were elevated and a higher percentage of increased levels of C-reactive protein and fibrinogen degradation products was found in the exposed group. Although no definite cause-effect relationship could be established, it is suggested that the responsible agent in the environment is endotoxins.
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A clinical investigation was made among workers in a sewage treatment plant and age matched controls not exposed to sewage. Acute incidences of fever and eye symptoms were found in about 50% of the exposed population. Serum immunoglobulins, white blood cells and thrombocytes were elevated in the exposed group. A higher percentage of increased levels of C-reactive protein and fibrinogen degradation products was found in the exposed group. Although no definite cause-effect relationship can be established the responsible agent in the environment could well be endotoxins.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.